Endometrial carcinoma: molecular alterations involved in tumor development and progression

A Yeramian, G Moreno-Bueno, X Dolcet, L Catasus… - Oncogene, 2013 - nature.com
… I tumors are low-grade and estrogen-related endometrioid endometrial carcinomas (EECs)
that usually develop in perimenopausal women and coexist or are preceded by endometrial

Endometrial carcinoma

A Di Cristofano, LH Ellenson - Annu. Rev. Pathol. Mech. Dis., 2007 - annualreviews.org
… As in other tumor systems, the molecular studies of endometrial cancer support the concept
that epithelial-derived tumors develop from preinvasive lesions that accrue a constellation of …

Pathology of endometrial carcinoma

SF Lax - Molecular Genetics of Endometrial Carcinoma, 2017 - Springer
… with low copy number changes and of hypermutated tumors was in between [22]. Recent
studies reported POLE mutations in endometrial carcinomas with an excellent prognosis …

Endometrial carcinoma

PG Rose - New England Journal of Medicine, 1996 - Mass Medical Soc
… the exposure of the endometrium to estrogen. Both granulosa-cell and theca-cell tumors of
the … 5 to 15 percent of patients with such tumors have a synchronous endometrial carcinoma. …

Endometrial carcinoma: molecular subtypes, precursors and the role of pathology in early diagnosis

J Huvila, J Pors, EF Thompson… - The Journal of …, 2021 - Wiley Online Library
… We also devote little attention in this review to the phenomenon of tumor progression,
whereby loss of MMR expression or abnormal (mutant pattern) p53 expression occurs after …

Molecular genetics of endometrial carcinoma

DW Bell, LH Ellenson - Annual Review of Pathology …, 2019 - annualreviews.org
… Uterine carcinosarcomas are aggressive cancers that usually present as large, polypoid
endometrial tumors that often protrude through the cervical os. They metastasize in a similar …

Molecular pathogenesis and prognostic factors in endometrial carcinoma

HB Salvesen, LA Akslen - Apmis, 2002 - Wiley Online Library
… Angiogenesis is a crucial factor for tumor development and progression. The ability of …
The fact that nulliparous women have a higher risk for developing endometrial carcinoma

Two pathogenetic types of endometrial carcinoma

JV Bokhman - Gynecologic oncology, 1983 - Elsevier
… the development of endometrial carcinoma determines the biological peculiarities of the
tumor… On the basis of a prospective study of 366 patients with endometrial carcinoma, the author …

Prognostic parameters of endometrial carcinoma

J Prat - Human pathology, 2004 - Elsevier
Endometrial carcinoma is the most common malignant tumor of the female genital tract in
the Western world. Approximately 80% of cases are well- to moderately differentiated (…

Prognostic factors in endometrial carcinoma

P Uharček - Journal of Obstetrics and Gynaecology Research, 2008 - Wiley Online Library
Endometrial carcinoma is the most common malignancy of … Although most endometrial
carcinomas are detected at low … and follow‐up of endometrial carcinoma patients, the importance …