Early assessment of lung cancer immunotherapy response via circulating tumor DNA
SB Goldberg, A Narayan, AJ Kole, RH Decker… - Clinical Cancer …, 2018 - AACR
… challenging to interpret because tumors often shrink slowly … tumor cell death in real time
by quantifying changes in circulating tumor DNA (ctDNA) levels could enable early assessment …
by quantifying changes in circulating tumor DNA (ctDNA) levels could enable early assessment …
Circulating tumor DNA as an early cancer detection tool
A Campos-Carrillo, JN Weitzel, P Sahoo… - Pharmacology & …, 2020 - Elsevier
Circulating tumor DNA holds substantial promise as an early detection biomarker, particularly
for cancers that do not have currently accepted screening methodologies, such as ovarian, …
for cancers that do not have currently accepted screening methodologies, such as ovarian, …
Circulating-tumor DNA as an early detection and diagnostic tool
… tumor change over time. One approach to identifying the spatial and temporal complexity of
tumors is the analysis of tumor DNA … multiple mutations to assess whether specific mutations, …
tumors is the analysis of tumor DNA … multiple mutations to assess whether specific mutations, …
Circulating tumor DNA: clinical monitoring and early detection
RB Corcoran - Annual Review of Cancer Biology, 2019 - annualreviews.org
… The ability to assess the presence, level, and composition of tumor DNA from a routine,
noninvasive blood draw has opened the door to a broad array of high-impact clinical applications…
noninvasive blood draw has opened the door to a broad array of high-impact clinical applications…
Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer
S Waldeck, J Mitschke, S Wiesemann… - Molecular …, 2022 - Wiley Online Library
… tumor DNA (ctDNA) has demonstrated great potential as a noninvasive biomarker to assess
minimal residual disease (MRD) and profile tumor … during and after tumor resection, or its …
minimal residual disease (MRD) and profile tumor … during and after tumor resection, or its …
Early assessment of molecular progression and response by whole-genome circulating tumor DNA in advanced solid tumors
… Treatment response assessment for patients with advanced solid tumors is complex and …
circulating tumor DNA (ctDNA) were used to assess response or resistance to treatment early in …
circulating tumor DNA (ctDNA) were used to assess response or resistance to treatment early in …
Monitoring daily dynamics of early tumor response to targeted therapy by detecting circulating tumor DNA in urine
H Husain, VO Melnikova, K Kosco, B Woodward… - Clinical cancer …, 2017 - AACR
… Purpose: Noninvasive drug biomarkers for the early assessment of tumor response can enable
… Circulating tumor DNA (ctDNA) is released into the circulation by tumor cell turnover and …
… Circulating tumor DNA (ctDNA) is released into the circulation by tumor cell turnover and …
[HTML][HTML] Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer
J Tie, I Kinde, Y Wang, HL Wong, J Roebert… - Annals of …, 2015 - Elsevier
… For each patient, one tumor mutation was selected to assess the presence and the level
of ctDNA in plasma samples using a digital genomic assay termed Safe-SeqS. …
of ctDNA in plasma samples using a digital genomic assay termed Safe-SeqS. …
[HTML][HTML] Circulating tumor DNA allele fraction: a candidate biological signal for multicancer early detection tests to assess the clinical significance of cancers
J Bredno, O Venn, X Chen, P Freese… - The American Journal of …, 2022 - Elsevier
… circulating tumor allele fraction (cTAF)], which could inform prognosis and help assess the
cancer's clinical significance. This review discusses the factors affecting circulating tumor DNA …
cancer's clinical significance. This review discusses the factors affecting circulating tumor DNA …
Role of circulating tumor DNA in the management of early‐stage lung cancer
H Zhao, KZ Chen, BG Hui, K Zhang, F Yang… - Thoracic …, 2018 - Wiley Online Library
… Circulating tumor DNA (ctDNA) is free DNA shed from tumor … High concordance between
ctDNA and tumor DNA plays a … be applied in early diagnosis and can be used to assess the …
ctDNA and tumor DNA plays a … be applied in early diagnosis and can be used to assess the …
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