Role of circulating-tumor DNA analysis in non-small cell lung cancer

T Jiang, S Ren, C Zhou - Lung Cancer, 2015 - Elsevier
… advanced non-small-cell lung cancer (NSCLC) allowed precise … for the entire tumor genome,
circulating tumor DNA (ctDNA) … of tumor burden, acquired resistance, tumor heterogeneity …

Analysis of circulating tumor DNA in plasma at diagnosis and during follow-up of lung cancer patients

G Sozzi, D Conte, L Mariani, S Lo Vullo, L Roz… - Cancer research, 2001 - AACR
… The results of this study provide straightforward evidence of an increased amount of tumor
circulating DNA in the plasma of lung cancer patients. To evaluate the accuracy of the DNA

[HTML][HTML] Circulating tumor cells versus circulating tumor DNA in lung cancer—which one will win?

S Calabuig-Farinas, E Jantus-Lewintre… - … lung cancer research, 2016 - ncbi.nlm.nih.gov
… In lung cancer liquid biopsies, blood samples are mainly used as a sample source for
analyzing circulating tumor cells (CTCs) or circulating tumor DNA (ctDNA), in addition to other …

Identification of circulating tumor DNA for the early detection of small-cell lung cancer

L Fernandez-Cuesta, S Perdomo, PH Avogbe… - …, 2016 - thelancet.com
… of circulating-tumor DNA (ctDNA) in cases diagnosed with small-cell lung cancer (SCLC). …
patients including those with early-stage tumors. Importantly, we also provide evidence that …

Perioperative dynamic changes in circulating tumor DNA in patients with lung cancer (DYNAMIC)

K Chen, H Zhao, Y Shi, F Yang, LT Wang, G Kang… - Clinical Cancer …, 2019 - AACR
… Circulating tumor DNA (ctDNA) are short DNA fragments providing a comprehensive view
of the tumor as were shed by tumor cells from multiple tumor regions (1). Application of ctDNA …

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

J Nong, Y Gong, Y Guan, X Yi, Y Yi, L Chang… - Nature …, 2018 - nature.com
… of 430 cancer-related genes in … tumor DNA sequencing is promising to delineate genomic
landscape, subclonal architecture and investigate genomic evolution of small-cell lung cancer

Circulating tumor DNA minimal residual disease detection of non–small-cell lung cancer treated with curative intent

B Pellini, AA Chaudhuri - Journal of Clinical Oncology, 2022 - ascopubs.org
… as non–small-cell lung cancer (NSCLC), these assays usually measure circulating tumor
DNA (ctDNA), which is composed of tumor-derived mutations in plasma cell-free DNA (cfDNA). …

Early assessment of lung cancer immunotherapy response via circulating tumor DNA

SB Goldberg, A Narayan, AJ Kole, RH Decker… - Clinical Cancer …, 2018 - AACR
… of lung cancer treatment by … tumor DNA (ctDNA) obtained from peripheral blood could be
used to predict immunotherapy response in patients with metastatic non–small cell lung cancer. …

A prospective study of circulating tumor DNA to guide matched targeted therapy in lung cancers

JK Sabari, M Offin, D Stephens, A Ni… - … the National Cancer …, 2019 - academic.oup.com
… non-small cell lung cancers as their tumors may harbor somatic … advanced non-small cell
lung cancer to targeted therapy and in … cell lung cancer in the real-world clinical practice setting. …

Early detection of molecular residual disease in localized lung cancer by circulating tumor DNA profiling

AA Chaudhuri, JJ Chabon, AF Lovejoy, AM Newman… - Cancer discovery, 2017 - AACR
… apply cancer personalized profiling by deep sequencing (CAPP-seq) circulating tumor
DNA … treated with curative intent for stage I–III lung cancer and 54 healthy adults. In 94% of …