Tumor heterogeneity: mechanisms and bases for a reliable application of molecular marker design

SJ Diaz-Cano - International journal of molecular sciences, 2012 - mdpi.com
Tumor heterogeneity is a confusing finding in the … This tumor heterogeneity is not
always a random and … The biologic reasons for this intratumoral heterogeneity would then …

Tumor heterogeneity: preclinical models, emerging technologies, and future applications

M Proietto, M Crippa, C Damiani, V Pasquale… - Frontiers in …, 2023 - frontiersin.org
… ’s role in tumor heterogeneity will be extensively … tumor heterogeneity and how the integrated
use of these models and technologies can improve our knowledge of tumor heterogeneity, …

Glioma: application of whole-tumor texture analysis of diffusion-weighted imaging for the evaluation of tumor heterogeneity

YJ Ryu, SH Choi, SJ Park, TJ Yun, JH Kim, CH Sohn - PloS one, 2014 - journals.plos.org
… [20] demonstrated the potential for CT texture analysis in quantifying tumor heterogeneity
in gliomas and showed a correlation between tumor heterogeneity and tumor grade. …

Assessing reliability of intra-tumor heterogeneity estimates from single sample whole exome sequencing data

J Abécassis, AS Hamy, C Laurent, B Sadacca… - PloS one, 2019 - journals.plos.org
… been proposed to estimate intra-tumor heterogeneity from whole exome sequencing (WES) …
systematically apply and compare 6 computational methods to estimate tumor heterogeneity

Tumor heterogeneity: does it matter?

C Turnquist, RA Watson, A Protheroe… - Expert Review of …, 2019 - Taylor & Francis
… of tumor heterogeneity in three main areas: prognostication, development of targeted
therapeutics and tumor … group), only two cell lines, and application to only one type of cancer. …

Imaging heterogeneity in lung cancer: techniques, applications, and challenges

U Bashir, MM Siddique, E Mclean… - American Journal of …, 2016 - Am Roentgen Ray Soc
… a role in characterizing tumors and predicting … heterogeneous tumors on imaging tend to
be more aggressive and to be associated with poorer outcomes and that tumor heterogeneity

Quantification of heterogeneity as a biomarker in tumor imaging: a systematic review

L Alic, WJ Niessen, JF Veenland - PloS one, 2014 - journals.plos.org
… quantification of tumor heterogeneity or tumor texture with the goal to differentiate between
… In pattern recognition applications, the rule of thumb is to use 5–10 datasets per feature per …

[HTML][HTML] Pre-analytics and tumor heterogeneity

S Bonin, G Stanta - New biotechnology, 2020 - Elsevier
… In Table 1 a summary of possible pitfalls in tumor molecular heterogeneity is presented in …
that intra-tumor heterogeneity cannot be evaluated where multiple or total tumor sampling has …

Imaging intratumor heterogeneity: role in therapy response, resistance, and clinical outcome

JPB O'Connor, CJ Rose, JC Waterton… - Clinical Cancer …, 2015 - AACR
… Most methods of analysis require hundreds to thousands of voxels for robust application. …
to tumor data and account for approximately half of studies measuring tumor heterogeneity (35)…

A system for tumor heterogeneity evaluation and diagnosis based on tumor markers measured routinely in the laboratory

L Hui, L Rixv, Z Xiuying - Clinical Biochemistry, 2015 - Elsevier
tumor heterogeneity can be used as a tool for effective tumor diagnosis. Analyzing tumor
heterogeneity with various tumor … of tumors, using which a biological tumor classification system …