… alterations in tumor cells, the tumor microenvironment (TME) has … Here, we propose that
the adaptive mechanisms of tumor … understanding of adaptive mechanisms driven by the TME …

… These two major phenotypes of tumor microenvironment may require distinct immunotherapeutic
… Understanding the mechanism by which the tumor microenvironment context promotes …

… cells into the circulatory system and can suppress antitumor immune mechanisms and responses
[7… by acting as messengers between the adaptive and innate systems. Furthermore, the …

… The adaptive immune system can be capable of recognizing … Major mechanisms by
which the tumor microenvironment modulates the response to therapy. Stromal cells, including …

… as well as adaptive antitumor immunity by a variety of mechanisms as discussed below. … ,
many mechanisms responsible for dysfunction of immune cells in the tumor microenvironment …

… This review will discuss and contrast two mechanisms of tumor immune escape leading
either to … mediated through modulation of the adaptive immune response against the tumor. …

… and acidic microenvironment, the tumor microenvironment … Tumors become infiltrated with
diverse adaptive and innate … is a common mechanism underlying tumor formation in several …

… The tumor microenvironment (TME) regulates essential tumor survival and promotion
functions. Interactions between the cellular and structural components of the TME allow cancer …

… key barrier: the immunosuppressive tumor microenvironment. Suppression of tumor-specific
T … inducible suppressive mechanisms that are triggered by the same anti-tumor inflammatory …

… both innate and adaptive immune responses can both promote tumor progression or mediate
… A deepened knowledge on mechanisms involved in tumor progression and invasiveness …