The role of the tumor-microenvironment in lung cancer-metastasis and its relationship to potential therapeutic targets
SL Wood, M Pernemalm, PA Crosbie… - Cancer treatment …, 2014 - Elsevier
… Lung cancer originates within a microenvironment characterized by high degrees of
vascularization and oxygenation. Uniquely lungs … risk factor for lung cancer development. …
vascularization and oxygenation. Uniquely lungs … risk factor for lung cancer development. …
The tumor microenvironment in non–small-cell lung cancer
EE Graves, A Maity, QT Le - Seminars in radiation oncology, 2010 - Elsevier
… both in vitro and in vivo, and it improves tumor oxygenation in A549 lung carcinoma xenografts.
Nelfinavir can also increase blood flow in tumors (Cerniglia and Maity, unpublished data, …
Nelfinavir can also increase blood flow in tumors (Cerniglia and Maity, unpublished data, …
Therapeutic implications of tumor microenvironment in lung cancer: focus on immune checkpoint blockade
C Genova, C Dellepiane, P Carrega… - Frontiers in …, 2022 - frontiersin.org
… Tumor microenvironment (TME) might influence response to immunotherapy due to its …
lung cancer from the perspective of TME pointed out a complex scenario where tumor …
lung cancer from the perspective of TME pointed out a complex scenario where tumor …
Tumor microenvironment characterization identifies two lung adenocarcinoma subtypes with specific immune and metabolic state
J Huang, J Li, S Zheng, Z Lu, Y Che, S Mao… - Cancer …, 2020 - Wiley Online Library
… 3.1 Landscape of TME cells in lung adenocarcinoma To analyze the landscape of tumor
stromal cells in lung adenocarcinoma, we collected a TCGA-LUAD dataset and a meta-GEO …
stromal cells in lung adenocarcinoma, we collected a TCGA-LUAD dataset and a meta-GEO …
A risk model developed based on tumor microenvironment predicts overall survival and associates with tumor immunity of patients with lung adenocarcinoma
J Wu, L Li, H Zhang, Y Zhao, H Zhang, S Wu, B Xu - Oncogene, 2021 - nature.com
… Tumor microenvironment (TME) has been reported to exhibit a crucial effect in lung cancer.
… overall survival (OS) of patients with lung adenocarcinoma (LUAD) based on these genes. …
… overall survival (OS) of patients with lung adenocarcinoma (LUAD) based on these genes. …
Computational staining of pathology images to study the tumor microenvironment in lung cancer
S Wang, R Rong, DM Yang, J Fujimoto, S Yan, L Cai… - Cancer research, 2020 - AACR
… Although this tool was developed in lung adenocarcinoma pathology images, our results …
and neck cancer, breast cancer, and lung cancer squamous cell carcinoma pathology image …
and neck cancer, breast cancer, and lung cancer squamous cell carcinoma pathology image …
[HTML][HTML] Immune profile of the tumor microenvironment and the identification of a four-gene signature for lung adenocarcinoma
T Fan, M Zhu, L Wang, Y Liu, H Tian, Y Zheng… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
… tumor microenvironment are key factors affecting the progression of lung adenocarcinomas
(… Using the cancer gene expression dataset from The Cancer Genome Atlas (TCGA) program…
(… Using the cancer gene expression dataset from The Cancer Genome Atlas (TCGA) program…
… transition is associated with a distinct tumor microenvironment including elevation of inflammatory signals and multiple immune checkpoints in lung adenocarcinoma
Y Lou, L Diao, ERP Cuentas, WL Denning, L Chen… - Clinical Cancer …, 2016 - AACR
… lung adenocarcinomas displaying a “mesenchymal” phenotype are associated with distinct
tumor microenvironment … preexisting immunity and increases in tumor infiltration by CD3 + T …
tumor microenvironment … preexisting immunity and increases in tumor infiltration by CD3 + T …
Analysis of prognostic genes in the tumor microenvironment of lung adenocarcinoma
Z Xu, M Zhao, W Chen, K Li, F Qin, W Xiang, Y Sun… - PeerJ, 2020 - peerj.com
… processes and the response of cancer to immunotherapy. Thus, … lung adenocarcinomas
(LUAD) using the ESTIMATE algorithm, which also significantly affects the prognosis of cancer. …
(LUAD) using the ESTIMATE algorithm, which also significantly affects the prognosis of cancer. …
Identification of key genes in the tumor microenvironment of lung adenocarcinoma
W Long, Q Li, J Zhang, H Xie - Medical Oncology, 2021 - Springer
… The tumor microenvironment plays an important role in tumor … with the microenvironment of
lung adenocarcinoma (LUAD). … cells in malignant tumors were downloaded from The Cancer …
lung adenocarcinoma (LUAD). … cells in malignant tumors were downloaded from The Cancer …
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