Therapeutic targeting of the tumor microenvironment
L Bejarano, MJC Jordāo, JA Joyce - Cancer discovery, 2021 - AACR
… analysis of the current therapies targeting the TME, combining a discussion of the underlying
basic biology with clinical evaluation of different therapeutic approaches, and highlighting …
basic biology with clinical evaluation of different therapeutic approaches, and highlighting …
[PDF][PDF] Therapeutic targeting of the tumor microenvironment
JA Joyce - Cancer cell, 2005 - cell.com
… between their tumor-inhibitory and tumor-… tumor microenvironment. Recent experi ments
have suggested various approaches to target different cell types in the tumor microenvironment, …
have suggested various approaches to target different cell types in the tumor microenvironment, …
Tumor microenvironment as a therapeutic target in cancer
Y Xiao, D Yu - Pharmacology & therapeutics, 2021 - Elsevier
… progress in targeting the tumor microenvironment in both … in targeting the tumor
microenvironment to achieve therapeutic … to better decipher the tumor microenvironment; and …
microenvironment to achieve therapeutic … to better decipher the tumor microenvironment; and …
Targeting tumor microenvironment for cancer therapy
C Roma-Rodrigues, R Mendes, PV Baptista… - International journal of …, 2019 - mdpi.com
… The improvement in the efficacy of cancer therapeutics will probably be based on the use
of combined therapies targeting all cell populations that cohabit in the TME. Novel tactics can …
of combined therapies targeting all cell populations that cohabit in the TME. Novel tactics can …
Targeting the tumor microenvironment for cancer therapy
… setting the targeting of the tumor microenvironment to … the tumor stroma, and the similarity
with normal tissue present huge challenges for therapies targeting the tumor microenvironment…
with normal tissue present huge challenges for therapies targeting the tumor microenvironment…
Tumor microenvironment targeted nanotherapeutics for cancer therapy and diagnosis: A review
S Thakkar, D Sharma, K Kalia, RK Tekade - Acta biomaterialia, 2020 - Elsevier
… We highlight the potential of tumor microenvironment; its role in disease progression, …
effective cancer therapy by conceptual understanding of tumor microenvironment and epigenetic …
effective cancer therapy by conceptual understanding of tumor microenvironment and epigenetic …
[HTML][HTML] Targeting the tumor microenvironment
PA Kenny, GY Lee, MJ Bissell - … in bioscience: a journal and virtual …, 2007 - ncbi.nlm.nih.gov
… synthesized in the breast tumor microenvironment by a “druggable” target. The third-… therapy
targeted at a component in the microenvironment resulting in strong efficacy against tumors …
targeted at a component in the microenvironment resulting in strong efficacy against tumors …
Regulatory T cells in the tumor microenvironment and cancer progression: role and therapeutic targeting
B Chaudhary, E Elkord - Vaccines, 2016 - mdpi.com
… therapies. In this review, we critically examine the role of Tregs in the tumor microenvironment
and … of current therapeutic modalities on Treg biology and the therapeutic opportunities for …
and … of current therapeutic modalities on Treg biology and the therapeutic opportunities for …
Therapeutic targeting of MicroRNAs in the tumor microenvironment
R Raue, AC Frank, SN Syed, B Brüne - International journal of molecular …, 2021 - mdpi.com
… Their drug RGLS5579 aims to target miR-10b in glioblastoma multiforme, where it has been
identified as a promising therapeutic target [311]. In their current study, they aim to confirm …
identified as a promising therapeutic target [311]. In their current study, they aim to confirm …
Advances in therapeutic targeting of cancer stem cells within the tumor microenvironment: an updated review
… targeting. In this updated review we revisit CSCs within the tumor microenvironment (TME)
and present novel treatment strategies targeting CSCs. These promising strategies include …
and present novel treatment strategies targeting CSCs. These promising strategies include …
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