… tumor microenvironment and discuss the potential clinical implications. As the microenvironment
… various components in the microenvironment in tumor progression, invasiveness, and …

… tumor microenvironment in both drug development and clinical trials; highlight challenges in
targeting the tumor microenvironment to … to better decipher the tumor microenvironment; and …

… , an immunotherapy-based treatment combination for treatment of metastatic pancreatic …
approved targeted therapies for treatment of advanced solid tumors. Although targeted therapies …

… , which were targeted on the highly proliferating mutated tumor cells, have been investigated.
The tumor microenvironment describes the non-cancerous cells in the tumor and has en…

… between their tumor-inhibitory and tumor-… tumor microenvironment. Recent experi ments
have suggested various approaches to target different cell types in the tumor microenvironment, …

… target the tumor microenvironment (TME) have emerged as a promising approach for cancer
treatment in recent years due to the critical roles of the TME in regulating tumor progression …

… an excellent target for microenvironment targeted therapy. … in the breast tumor
microenvironment by a “druggable” target. The … a therapy targeted at a component in the …

… sites and in their constituents can potentially be targeted to treat cancer. The significance
of the TME in the development of new cancer management regimens is becoming apparent, …

… tumor microenvironment; its role in disease progression, opportunities, challenges, and allied
treatment … therapy by conceptual understanding of tumor microenvironment and epigenetic …

… of the malignant tumor microenvironment which have been targeted for effective … tumor
microenvironment to facilitate better uptake of nano-chemotherapeutics (Figure 2) and (ii) Tumor …