Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells
U Testa, E Pelosi, G Castelli - Medical Sciences, 2018 - mdpi.com
… Most colorectal cancer occurrences are sporadic, not related to genetic predisposition or …
with colorectal cancer have a family history of colorectal cancer and 5% of these tumors arise in …
with colorectal cancer have a family history of colorectal cancer and 5% of these tumors arise in …
Variable β-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
T Brabletz, A Jung, S Reu, M Porzner… - Proceedings of the …, 2001 - National Acad Sciences
… an important driving force for progression of well-differentiated colorectal carcinomas is the
specific … transition processes by modulating intracellular β-catenin distribution in tumor cells. …
specific … transition processes by modulating intracellular β-catenin distribution in tumor cells. …
Oxidative stress and tumor progression in colorectal cancer
T Inokuma, M Haraguchi, F Fujita… - Hepato …, 2009 - nagasaki-u.repo.nii.ac.jp
… In conclusion, it may be possible to prevent tumor progression by regulating ROS, which
enhance cell proliferation and apoptosis suppression. For example, one possible therapeutic …
enhance cell proliferation and apoptosis suppression. For example, one possible therapeutic …
MicroRNA–mRNA interactions in colorectal cancer and their role in tumor progression
R Amirkhah, U Schmitz, M Linnebacher… - … and Cancer, 2015 - Wiley Online Library
… with different diseases, including colorectal cancer (CRC). Recent evidence indicates that
aberrant miRNA expression is tightly linked with the initiation and progression of CRC. To …
aberrant miRNA expression is tightly linked with the initiation and progression of CRC. To …
Expression of CD44 variant proteins in human colorectal cancer is related to tumor progression
VJM Wielenga, KH Heider, G Johan, A Offerhaus… - Cancer research, 1993 - AACR
… of tumor progression, ie, to the histological tumor grade. … v6, in colorectal cancer is strongly
related to tumor progression … play a role in human colorectal tumor metastasis similar to that in …
related to tumor progression … play a role in human colorectal tumor metastasis similar to that in …
Intratumoral macrophage counts correlate with tumor progression in colorectal cancer
JC Kang, JS Chen, CH Lee, JJ Chang… - Journal of surgical …, 2010 - Wiley Online Library
… tumor progression. Hence, we further tested whether colon cancer cells cocultured with
macrophages affected tumor … Since migration and invasion are required for tumor progression, …
macrophages affected tumor … Since migration and invasion are required for tumor progression, …
The role of gelatinases in colorectal cancer progression and metastasis
ORF Mook, WM Frederiks, CJF Van Noorden - … (BBA)-Reviews on Cancer, 2004 - Elsevier
… to be key events in tumor progression. Detection of TIMP-1 … tumor progression as well,
probably due to their growth factor-like properties [26]. Quenched substrate hydrolysis by tumor …
probably due to their growth factor-like properties [26]. Quenched substrate hydrolysis by tumor …
Oncogenic events regulate tissue factor expression in colorectal cancer cells: implications for tumor progression and angiogenesis
JL Yu, L May, V Lhotak, S Shahrzad, S Shirasawa… - Blood, 2005 - ashpublications.org
… tumor progression, but their causes have been elusive. We now report that in human colorectal
cancer … disease progression (activation of K-ras oncogene and inactivation of the p53 …
cancer … disease progression (activation of K-ras oncogene and inactivation of the p53 …
Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer
HM Meng, P Zheng, XY Wang, C Liu… - Cancer biology & …, 2010 - Taylor & Francis
… in colorectal cancer (CRC). Immunohistochemical analysis of 175 colorectal tumor samples
… Nanog functions as an inducer and also a recipient of EMT in tumor progression of CRC. …
… Nanog functions as an inducer and also a recipient of EMT in tumor progression of CRC. …
Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer
LY OuYang, XJ Wu, SB Ye, R Zhang, ZL Li… - Journal of translational …, 2015 - Springer
… In this study, we examined the correlation between MDSCs and tumor progression in CRC
patients and during routine treatment. We also studied how MDSCs interact with T cells and …
patients and during routine treatment. We also studied how MDSCs interact with T cells and …
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