Semaphorins in angiogenesis and tumor progression

G Neufeld, AD Sabag… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
… the effects of different semaphorins on angiogenesis and tumor progression, and had …
mechanisms by which different semaphorins affect angiogenesis and tumor progression. …

The semaphorins and their receptors as modulators of tumor progression

G Neufeld, Y Mumblat, T Smolkin, S Toledano… - Drug Resistance …, 2016 - Elsevier
… and inhibition or promotion of tumor angiogenesis and tumor lymphangiogenesis. This
review focuses on the diverse mechanisms by which semaphorins affect tumor progression. …

Semaphorins and tumor angiogenesis

G Serini, F Maione, F Bussolino - Angiogenesis, 2009 - Springer
… An increase in the autocrine VEGF-A/Sema3A ratio in ECs could contribute to the defects
of tumor blood vessels and support cancer progression. Treating cancers with anti-angiogenic

[HTML][HTML] Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models

F Maione, F Molla, C Meda, R Latini… - The Journal of …, 2009 - Am Soc Clin Investig
… , including members of the semaphorin family. By analyzing 3 … angiogenesis, semaphorin
3A (Sema3A) is expressed in ECs, where it serves as an endogenous inhibitor of angiogenesis

Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models

A Casazza, X Fu, I Johansson… - … , and vascular biology, 2011 - Am Heart Assoc
… The role of semaphorins in tumor progression is still poorly understood. In this study, we
aimed at elucidating the regulatory role of semaphorin 3A (SEMA3A) in primary tumor growth

[HTML][HTML] Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer

A Sakurai, C Doci, JS Gutkind - Cell research, 2012 - nature.com
… Similar to other Sema3s, the Sema3F-mediated suppression of tumor growth was associated
with an anti-angiogenic phenotype, where Sema3F expression significantly decreased the …

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

JR Sierra, S Corso, L Caione, V Cepero… - The Journal of …, 2008 - rupress.org
… the semaphorin in the tumor stroma are the tumor-associated macrophages (TAMs), and that
TAM-derived Sema4D is critical for tumor angiogenesistumor growth and angiogenesis) by …

Semaphorin receptors meet receptor tyrosine kinases on the way of tumor progression

G Cagnoni, L Tamagnone - Oncogene, 2014 - nature.com
… In particular, two monoclonal antibodies targeting the extracellular domain of Nrp1 inhibited
tumor angiogenesis and tumor growth in preclinical models. Notably, only one of these …

RETRACTED ARTICLE: Semaphorin 4D cooperates with VEGF to promote angiogenesis and tumor progression

H Zhou, NO Binmadi, YH Yang, P Proia, JR Basile - Angiogenesis, 2012 - Springer
… /Plexin-B1 system to tumor-induced angiogenesis when compared to VEGF and demonstrate
… for anti-angiogenic therapy of HNSCC and other solid tumors exhibiting insensitivity to anti-…

Regulation of angiogenesis and tumor progression by semaphorins

G Neufeld, AD Sabag, Y Mumblat, T Smolkin… - Semaphorins: A …, 2015 - Springer
… cells capable of modulating tumor progression into the tumor microenvironment. In this review…
which semaphorins modulate tumor progression, excluding the effects of the semaphorins