… study to determine whether tumor growth inhibition by the combination of radiation and
anti-VEGF mAb is dependent on tumor oxygen levels. To discern the role of tumor oxygenation, …

… tumor control (1). Biological approaches that use growth factor inhibitors to modify tumor
proliferation and/or radiosensitivity offer potential for improving tumor control. The EGFR …

… Evidence is rapidly mounting that dysregulated epidermal growth factor receptor (EGFR) …
tumor behavior and increased tumor resistance to cytotoxic agents, including radiotherapy (RT). …

… on the response of tumors to radiotherapy in … growth factors on the response of tumors to
ionizing radiation. In addition, we have for the first time quantified the effect of SU6668 on tumor …

… Growing evidence suggests that epidermal growth factor family receptors (HERs) play a
significant role in radiation response. … A phase 3 randomized trial in head and neck cancer is …

… of several angiogenic factors, including vascular endothelial growth factor (VEGF), interleukin
8, and basic fibroblast growth factor in A431 and human transitional cell carcinoma of the …

… Erlotinib (Tarceva) is an orally available HER1 (epidermal growth factor receptor, … radiation
response and investigate specific mechanisms underlying these interactions in human tumor …

… the in vitro and in vivo radiation response of human SCC tumor cells and xenografts, and …
to the enhanced radiation response induced by C225. Tumor xenograft studies demonstrated …

… of tumor VEGF secretion by IR affects the antitumor response, we treated LLC tumors with
… Female C57BL/6 mice bearing LLC tumors were divided into experimental groups and …

… growth factor (VEGF)/VEGFR2 pathway in tumor angiogenesis is supported by numerous
studies, including those that show inhibition of tumor growth in … Radiation represents a central …