… They neutralize VEGF-A, resulting in prevention of tumor angiogenesis. VEGFR tyrosine …
tumor therapy by inhibiting VEGFR signaling. Anti-VEGF drugs are a promising therapy for …

… in designing new drug therapies to target FGF receptor (… endothelial growth factor (VEGF) to
amplify tumor angiogenesis… tumor growth and angiogenesis than targeting either factor alone…

… of radiation markedly enhanced the therapeutic efficacy in all … ) tumors growing sc on BALB/c
nu/nu mice. This study shows that radiation is an integral component of local tumor therapy …

… tumor angiogenesis are regulated by a host of growth factors … others, such as basic fibroblast
growth factor (bFGF) and the … Activating factors can be produced by the tumors themselves…

… of growth factor receptor pathways that promote tumor angiogenesis. … growth factor (VEGF)
family of proteins and receptors. … with tumor progression and poor prognosis in several tumor …

… of tumor cells. In vivo, PTK787/ZK 222584 inhibited VEGFinduced angiogenesis in a growth
factor implant model as well as tumor … the subcutaneous growth of a variety of human tumor …

… platelet-derived growth factor (PDGF) superfamily of growth factors. Other members of the
VEGF family include VEGF-B, VEGF-C, VEGF-D, and VEGF-E and placenta growth factor (PlGF…

… is the vascular endothelial growth factor (VEGF, also known as vascular permeability factor
[VPF], or … Vascular endothelial growth factor is both a vascular growth factor and a vascular …

… therapy of the dual epidermal growth factor … tumor in phase II clinical trial (NCT00326495).
Secondly, aberrant expression of VEGFR and genetic alteration of fibroblast growth factor …

… to most existing therapies. Past studies have shown that connective tissue growth factor (CTGF) …
and how CTGF influences tumor growth, we generated pancreatic tumor cell lines that …