… fluids play in metastasis, including the forces and stresses that are utilised by circulating tumour
cells & tumour… by the role of physiological fluids and their mechanics in the biology of the …

… , integrating physics and mechanics with genomic investigations of … In this review, we outline
the role of fluid mechanics as an … tumor cell and release therapeutic agents inside the cells. …

… , we describe how circulating tumour cells and tumour-associated factors leverage bodily
fluids, their … , the influence of fluid mechanics on intravasation in early versus advanced primary …

… During invasion and metastasis, alterations in cell-cell adhesion between individual tumour
cells are key to driving the process. Existing experimental data suggests that tumour cell-…

… impact on tumour cells as will be described in this review. The mechanical microenvironment
may … of oncogenic pathways and inhibition of tumour suppressor genes. In addition, the …

… tumor cell glycocalyx thickness, and interstitial fluid flow velocity were incorporated into the
model to calculate the fluid and solid stresses on the cell … incorporated mechanical fluid forces …

… As in [22], we view the tumour as a two-phase material, consisting of tumour cells and …
repulsion with the relief of mechanical stress caused by deformation of the cellular membrane. Our …

… and model cancer cell mechanics. By reviewing the experimental studies that compared the
… and the spring constant of tumour cells are lower than those of normal cells and that in a …

… In this Review , we describe how circulating tumour cells and tumour- associated factors …
Fluid mechanics in primary tumours Solid tumours form a complex microenvironment con…

… The 2D numerical studies on tumour cell adhesion in curved microvessels revealed that
the … tumour cells and localised shear stresses and their gradients would also affect the cell …