… -derived tumour organoids (PDOs) have revolutionised our understanding of cancer biology
… and morphological characteristics of parental tumours. Given these characteristics, PDOs (…

… These reports highlight cancer organoid maintenance of parent tumour biology, including
(epi)… Despite their potential as valuable models of patient-specific cancer biology, organoids …

… to manipulate tumour organoids further improves the utility of this culture system in cancer
… Analysis has uncovered new understanding of cancer biology and disease pathogenesis. In …

… Here, we report methodologies for the establishment of PDX-tumour organoids, … tumour/organoid
and CLOs we assessed the transcriptomic signature of the PT127 PDX-derived tumour …

… tumour organoid protocols and how they can be utilized as an alternative model for cancer
… We highlight the approaches to exploit patient-derived tumour organoid biobanks for drug …

… In several cancers including those from the mammary gland, the development of human
tumour organoids has proved more challenging than generating organoids from mouse cells. …

… tumour organoid models that capture important immune features of the TME. We highlight
diverse opportunities for organoid-based investigations of tumour … model cancer biology and …

… tumor organoids). In addition, tumor-derived organoids can be used directly in basic cancer
biology … More broadly, collections of diseased organoids can be stored in biobanks and used …

… tumour organoids are normal organoids which are gene-edited to be mutated into tumour
organoids … gene editing and organoid culture is used to derive tumour organoids. Manato, M et …

… Tumour cells isolated from liquid samples such as peripheral blood 51 , ascites 49,52 and
… starting material to generate organoids. Patient-derived tumour organoids can be generated …