… Influence of the UCHL1-HIF-1 axis on radiosensitivity of EMT6 cells. (a) The clonogenic
survival assay with the indicated dose of X-irradiation was performed using EMT6 cells …

… of melittin on tumor growth and radiosensitivity in vivo using a … Hypoxia-inducible factor
1-alpha (HIF-1α), the major concern of HIF, is an important regulatory factor that enables tumor …

… 1, a specific inhibitor of HIF-1{alpha}. Consequently, our results suggest that the radiosensitivity
of tumor … overexpression of HIF-1{alpha} dependent on the alteration of intracellular GSH …

… a promising strategy for cancer therapy in combination with radiation. Our study showed that
HIF-1α inhibitor PX-478 enhanced the radiosensitivity of prostate carcinoma cells irradiated …

… HIF1A gene expression data for 171 esophageal cancers … that HIF-1A was expressed at a
significantly higher level in tumor … tumor tissues and para-carcinoma tissues from esophageal …

… hypoxia inducible factor-1 (HIF-1). There are currently several classes of agents that may
increase tumor radiosensitivity … of cancer cell metabolism by hypoxia-inducible factor 1. Semin …

… to identify inhibitors of the HIF-1 pathway 9,10 , but to our knowledge, no high-throughput
screens designed to identify novel inhibitors of the OCR in cancer cells have been published. …

… By dissecting the impact of hypoxia-inducible factor 1 alpha on molecular responses, this …
As a result, HIF-1α was proposed as a marker for radiosensitivity. Hypoxia/reoxygenation …

… However, this effect of statins in prostate cancer remains unclear. In the … on HIF-1α expression
and radiosensitivity in prostate cancer cells. The hypoxia-induced human prostate cancer …

… Conclusions: The expression of HIF-1alpha can be stably blocked by RNAi. A549/HIF-1alpha(-)
tumors appear to be more radiosensitive than A549 tumors. (authors) …