… into the tumour, leading the light directly into the tumour tissue. Also, the intra-operative
application of PDT to treat and “mop-up” the tumour bed of any remaining tumour cells has been …

… In addition to destroying tumour tissue by a process that can produce cellular necrosis and
… to treated tumours. PDT might increase the immunogenicity of dead tumour cells by exposing …

… The treatment consists in the application of a PS, which selectively accumulates in the
tumour tissue, followed by subsequent exposition to light of an appropriate wavelength (generally …

… cells with relative sparing of porphyrin-free normal tissues in vivo. In particular, photodynamic
therapy should offer a unique approach to the treatment of brain tumours, since (a) …

… of necrosis in experimental tumours relative to Photofrin, … in tumour tissue required to achieve
tumour control (high … based on relative tissue levels between tumour and normal tissue [23])…

… Photodynamic therapy (PDT) is a cancer treatment modality that is based on the … is retained
in tumour tissues more than in normal tissues, followed by illumination of the tumour with vis…

… a post-doctoral fellow working on tumour microcirculation and photodynamic therapy (PDT). …
His main interests are fluorescence diagnosis, the mechanism of action of PDT and tumour …

… for tumour destruction in photodynamic therapy: (i) direct damage to tumour cells; (ii) … -localising
effect of porphyrins used for the photodynamic therapy of cancer has been the subject of …

… The therapy, as used in cancer treatment, is based on the preferential uptake and/or
retention of a photosensitizer in the tumour tissue and the cytotoxic effects of the photosensitizer …

… Photofrin-based photodynamic therapy (PDT) was investigated using mouse tumour models
… PDT light treatment of subcutaneously growing tumours, markedly enhanced the cure rate …