… significantly to the risk score model. A final type 1 diabetes risk score was then derived from
… The change in the type 1 diabetes risk score from baseline to 1 year was in itself also highly …

… type 1 diabetes (T1D) genetic risk score (GRS) to predict progression of islet autoimmunity
and T1D in at-risk … -1 Risk Score, age, number of positive autoantibodies, sex, and ethnicity (…

… Genotyping these variants and combining the risk of each inherited allele to create a type
1 diabetes genetic risk score (T1D-GRS) allows us to accurately capture an individual’s …

… Since the selection of participants for type 1 diabetes (T1D) prevention trials is based in
large part on risk estimation, it is important to classify risk as accurately as possible. Study …

… risk score that incorporates levels of multiple islet autoantibodies could enhance the prediction
of type 1 diabetes … been shown to be predictive of type 1 diabetes (T1D) (1–8). For the …

… In 6,481 case and 9,247 control subjects from the Type 1 Diabetes Genetics Consortium, …
diabetes classification and sought to provide a framework for comparison with previous scores…

… In this study, we assessed whether a genetic risk score (GRS) could provide a simple and
inexpensive test for the classification of diabetes. Although the classification of T1D and T2D is …

… individuals at greatest risk of impending … risk by developing a combined risk score
incorporating both fixed and variable factors (genetic, clinical and immunological) in 7,798 high-risk …

… associated with type 1 diabetes risk in … of type 1 diabetes risk (area under the curve 0.871),
performing significantly better than a European-based GRS and two polygenic risk scores in …

… We developed a type 1 diabetes risk score (Diabetes Prevention Trial–Type 1 … of type 1
diabetes have been studied (8,9), but the DPTRS is the first risk score for type 1 diabetes that has …