Systematic review of polygenic risk scores for type 1 and type 2 diabetes

F Padilla-Martínez, F Collin, M Kwasniewski… - International journal of …, 2020 - mdpi.com
… We selected 15 risk scores from three … risk scores that discriminate between type 1 diabetes
patients and healthy people, one that discriminate between type 1 and type 2 diabetes, two …

Genetic risk factors for type 1 diabetes

F Pociot, Å Lernmark - The Lancet, 2016 - thelancet.com
… We calculated a risk score on the basis of the genotype at all loci and for HLA only by logistic
regression, and plotted the proportion of all cases that score greater than any given cutoff (…

Stratification of type 1 diabetes risk on the basis of islet autoantibody characteristics

P Achenbach, K Warncke, J Reiter, HE Naserke… - Diabetes, 2004 - Am Diabetes Assoc
… (6,13), thereby limiting the use of autoantibody testing alone for accurate risk assessment.
We also found that up to 30% of relatives positive for three autoantibodies are likely to be …

Type 1 diabetes

D Daneman - The Lancet, 2006 - thelancet.com
… and mortality associated with type 1 diabetes. Newer treatment approaches have facilitated
improved outcomes in terms of both glycaemic control and reduced risks for development of …

The TrialNet Natural History Study of the Development of Type 1 Diabetes: objectives, design, and initial results

…, Type 1 Diabetes TrialNet Study Group - … diabetes, 2009 - Wiley Online Library
risk assessment) includes oral glucose tolerance tests (OGTTs) in antibody-positive subjects
and estimation of 5-yr diabetes risks … assays of novel type 1 diabetes risk markers. The …

Diabetes risk score: towards earlier detection of type 2 diabetes in general practice

SJ Griffin, PS Little, CN Hales… - Diabetes/metabolism …, 2000 - Wiley Online Library
1, a risk score was first developed in a notional sample derived from two studies of newly
diagnosed Type 2 diabetes, … The score was derived from data collected on a range of predictor …

Insulin resistance is a risk factor for progression to type 1 diabetes

S Fourlanos, P Narendran, GB Byrnes, PG Colman… - Diabetologia, 2004 - Springer
… has been documented in established Type 1 diabetes [6] and … of Type 1 diabetes [9, 10].
First-degree relatives positive for islet antibodies who are at increased risk of Type 1 diabetes

Deficiencies of cardiovascular risk prediction models for type 1 diabetes

JC Zgibor, GA Piatt, K Ruppert, TJ Orchard… - Diabetes …, 2006 - Am Diabetes Assoc
… The purpose of developing these functions and risk scores is to estimate the “global risk” or
type 1 diabetes suffer a disproportionate risk for CAD compared with those without diabetes. …

Suicide risk assessment in youth and young adults with type 1 diabetes

S Majidi, HK O'Donnell, K Stanek, E Youngkin… - Diabetes …, 2020 - Am Diabetes Assoc
type 1 diabetes are at 61% higher risk of reporting suicidal ideations, compared with individuals
without type 1 diabetes (9) and youth with type 1 diabetes … suicide risk assessment used …

Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review

RA Watkins, C Evans-Molina, JS Blum… - Translational …, 2014 - Elsevier
… Although diabetes risk scores establish a probability of the eventual clinical onset of T1D, …
These markers can, potentially, be incorporated into screening Ab's and risk scores. …