Preventing type 1 diabetes in childhood

CM Dayan, REJ Besser, RA Oram, W Hagopian… - Science, 2021 - science.org
Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing β cells of
… islet autoantibodies, combined with genetic risk assessment, can identify most children who …

Genetics of type 1 diabetes

MJ Redondo, AK Steck, A Pugliese - Pediatric diabetes, 2018 - Wiley Online Library
One of the current challenges is how to integrate the wealth of knowledge about T1D
genetics and apply it meaningfully for diagnosis and risk assessment. For the last 15 years, …

A strategy for combining minor genetic susceptibility genes to improve prediction of disease in type 1 diabetes

C Winkler, J Krumsiek, J Lempainen, P Achenbach… - Genes & …, 2012 - nature.com
… We further applied a novel analysis of combinatorial gene risk assessment that aided in …
Because the total set of genes examined proved effective in type 1 diabetes risk stratification, we …

[HTML][HTML] Risk factors for cardiovascular disease in type 1 diabetes

Diabetes Control and Complications Trial… - Diabetes, 2016 - ncbi.nlm.nih.gov
… well-established in type 2 but not type 1 diabetes (T1DM). We assessed risk factors in the
long… subject who experienced an event has a higher risk score than a subject who is event free. …

[HTML][HTML] Microalbuminuria in type 1 diabetes: rates, risk factors and glycemic threshold

N Chaturvedi, S Bandinelli, R Mangili, G Penno… - Kidney international, 2001 - Elsevier
… seriously affect the assessment of risk factor relationships. … risk of microalbuminuria remains
high in type 1 diabetes and that glycemic control is one of the strongest predictors of this risk, …

Diabetes risk score in the United Arab Emirates: a screening tool for the early detection of type 2 diabetes mellitus

N Sulaiman, I Mahmoud, A Hussein… - BMJ Open Diabetes …, 2018 - drc.bmj.com
… women with gestational diabetes in their model unlike most other risk scores. However, the
… in the Saudi Diabetes Risk Score. However, smoking did not contribute to our score. This is …

Pathogenesis of type 1 diabetes: lessons from natural history studies of high‐risk individuals

N Nokoff, M Rewers - Annals of the New York Academy of …, 2013 - Wiley Online Library
Type 1 diabetes (T1D) is an autoimmune disease characterized by known genetic risk
factors with T cell–mediated infiltration and destruction of the beta cells within pancreatic islets. …

Trabecular bone score in type 1 diabetes—a cross-sectional study

T Neumann, S Lodes, B Kästner, T Lehmann… - Osteoporosis …, 2016 - Springer
… Table 1 Baseline characteristics, bone mineral density (BMD), and trabecular bone score
(TBS) in controls and patients with type 1 diabetes (T1D). Results are presented as mean ± …

Suicide risk in type 1 diabetes mellitus: a systematic review

M Pompili, A Forte, D Lester, D Erbuto, F Rovedi… - Journal of …, 2014 - Elsevier
risk assessment of patients with DM-1 should be part of the routine clinical assessment. The
… that a suicide risk assessment of patients with DM-1 should be part of the routine clinical …

[PDF][PDF] Indian diabetes risk score

SR Joshi - JAPI, 2005 - researchgate.net
… CVD risk score are sex, age, total cholesterol, smoking history, systolic blood pressure while
those of diabetic risk score are age, sex, BMI/WHR and family history of diabetes. The odds …