… immune response, self antigen–induced immune response, and microbial translocation on chronic immune activation in successfully treated HIV type 1infected …

L Wittkop, J Bitard, E Lazaro, D Neau… - … Journal of infectious …, 2013 - academic.oup.com
… The contribution of each of these mechanisms to chronic immune activation is not … immune
activation in these patients because of its prevalence, the intensity of the immune response to …

Immune activation in the course of HIV‐1 infection: causes, phenotypes and persistence under therapy

M Younas, C Psomas, J Reynes, P Corbeau - HIV medicine, 2016 - Wiley Online Library
immune activation in the course of HIV-1 infection. In this review we will discuss the various
causes of immune activation in HIV-1 infected … and dysregulation of the immune system, and/…

Impaired primary immune response in type-1 diabetes: results from a controlled vaccination study

N Eibl, M Spatz, GF Fischer, WR Mayr, A Samstag… - Clinical …, 2002 - Elsevier
… Our results do indeed demonstrate a significant impairment of the humoral immune response
in type-1 diabetes patients. This impairment, however, could only be observed with primary …

Immune response of T cells during herpes simplex virus type 1 (HSV-1) infection

J Zhang, H Liu, B Wei - Journal of Zhejiang University-Science B, 2017 - Springer
immunity and are important for clearing HSV-1. In this review, we examine the findings on T
cell immune responses during HSV-1 infection, … design of new vaccine candidates for HSV-1. …

The immune response to herpes simplex virus type 1 infection in susceptible mice is a major cause of central nervous system pathology resulting in fatal encephalitis

P Lundberg, C Ramakrishna, J Brown… - Journal of …, 2008 - Am Soc Microbiol
… This study was undertaken to investigate possible immune mechanisms in fatal herpes
simplex virus type 1 (HSV-1) encephalitis (HSE) after HSV-1 corneal inoculation. Susceptible …

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis

A Boasso, GM Shearer - Clinical immunology, 2008 - Elsevier
immune activation hypothesis, in which HIV infection primarily induces chronic activation of
innate immune … , despite the persistence of an activated T cell phenotype. This imbalanced …

… levels of chronic immune activation in the T-cell compartments of patients coinfected with hepatitis C virus and human immunodeficiency virus type 1 and on highly …

VD Gonzalez, K Falconer, KG Blom, O Reichard… - Journal of …, 2009 - Am Soc Microbiol
… Chronic immune activation is a driver of human immunodeficiency virus type 1 (HIV-1) … virus
(HCV)/HIV-1 coinfection display sharply elevated immune activation as determined by CD38 …

Reduced Immune Activation and T Cell Apoptosis in Human Immunodeficiency Virus Type 2 Compared with Type 1: Correlation of T Cell Apoptosis with β2 …

P Michel, AT Balde, C Roussilhon… - … Journal of infectious …, 2000 - academic.oup.com
… This study analyzes the degree of immune activation and … or patients infected with human
immunodeficiency virus (HIV)-1 or … -1-infected donors is associated with lower levels of immune

The induction of a type 1 immune response following a Trypanosoma brucei infection is MyD88 dependent

MB Drennan, B Stijlemans… - The Journal of …, 2005 - journals.aai.org
… The initial host response toward the extracellular … with a type 1 immune response. In this
study, we show that this inflammatory response is dependent on activation of the innate immune

Evidence for innate immune system Activation in HIV type 1infected elite controllers

S Krishnan, EMP Wilson, V Sheikh… - … Journal of infectious …, 2014 - academic.oup.com
Type 1 IFN–Inducible Gene Expression To investigate the possible origin of this immune
activation, we looked at the type I IFIG profile in a subset of participants from all 3 groups. …