… IFN-High SLE patients. Consistent with this, our study linking type I IFNs to CD8 + T metabolic
fitness … the underlying disease mechanisms between IFN-High and IFN-Neg SLE patients …

… We also examined type 1 IFN induced changes in CD8 + T cell metabolism. In these cells,
IL-15 stimulates differentiation into memory cells that is coupled to, and dependent upon, …

… metabolic change impacts interferon production. We describe how glycolysis, lipid metabolism
(… - linked intermediates itaconate and fumarate impact type I interferons. Targeting these …

… an IFN-induced rewiring of the cellular metabolism. In this review, we discuss the roles of
type I and type II IFNs in regulating the cellular metabolism … affect these metabolic activities to …

… This prompted us to investigate, whether IFN-I alone is sufficient to regulate metabolic
pathways in hepatocytes. To this end, we isolated primary hepatocytes from C57Bl/6J (wild type) …

… of the antiviral response based on the type I and III IFN systems that aims to optimally clear
viral infections without activating inflammation unnecessarily and compromising host fitness. …

… survive polyamine depletion through selecting for mutations that elevate viral fitness. While
targeting host cell metabolism provides a unique opportunity to restrict viral propagation, one …

… Thus, Treg cells indirectly but selectively sustained M2-like TAM metabolic fitness, …
their modulation of lipid metabolism in M2-like TAMs could improve cancer immunotherapy. …

… Reduced metabolic fitness of Ifnar1 −/− cDCs cannot be … and IFN-I receptor (IFNAR)-deficient
mice, we found that tonic IFNAR signaling instructs a specific epigenomic and metabolic …

… ablation of type I interferon signalling and … interferon-α and -β receptor 1 (IFNAR1) signalling
was required for T cell activation and proliferation and the modulation of lipid metabolism, …