[HTML][HTML] Tyrosinase inhibitors naturally present in plants and synthetic modifications of these natural products as anti-melanogenic agents: a review

M Hassan, S Shahzadi, A Kloczkowski - Molecules, 2023 - mdpi.com
… The basic aim of this article is to review various novel tyrosinase inhibitors which have been
… Additionally, another significant aspect is the development of skin whitening agents which is …

Natural sources of melanogenic inhibitors: A systematic review

CF Goelzer Neto, P do Nascimento… - … Journal of Cosmetic …, 2022 - Wiley Online Library
… natural agents; tyrosinase inhibition AND natural agents; melanogenesis AND tyrosinase
inhibition), … aristata extract as a new candidate anti-melanogenic agent that could be used as a …

Tyrosinase inhibitors from natural and synthetic sources as skin-lightening agents

MN Masum, K Yamauchi, T Mitsunaga - Reviews in Agricultural …, 2019 - jstage.jst.go.jp
… , inhibition of tyrosinase, is the prime target for researchers to regulate melanin production.
Tyrosinase inhibitors … In this review, we focus on the recent advances of tyrosinase inhibitors

Melanogenesis inhibitors: Strategies for searching for and evaluation of active compounds

A Gunia-Krzyżak, J Popiol… - Current medicinal …, 2016 - ingentaconnect.com
… In vitro tests of tyrosinase inhibition using Ltyrosine or L-DOPA as a substrate serve to find …
depigmenting agent, it was not clear why kojic acid does not show anti-melanogenic activity in …

Skin whitening agents: Medicinal chemistry perspective of tyrosinase inhibitors

T Pillaiyar, M Manickam… - … of enzyme inhibition and …, 2017 - Taylor & Francis
… From the structural point of view, a “linear” β-phenyl-α,β-unsaturated carbonyl scaffold
plays an essential role in showing anti-melanogenic effect through the direct inhibition of …

Evaluation of in vitro and in vivo anti-melanogenic activity of a newly synthesized strong tyrosinase inhibitor (E)-3-(2, 4 dihydroxybenzylidene) pyrrolidine-2, 5-dione (3 …

KW Chung, YJ Park, YJ Choi, MH Park, YM Ha… - … et Biophysica Acta (BBA …, 2012 - Elsevier
… In summary, we identified 3-DBP as a novel anti-melanogenic agent in both in vitro and in
vivo. The compound appears to decrease melanogenesis stimulated by α-MSH through non-…

Exploiting the 1-(4-fluorobenzyl) piperazine fragment for the development of novel tyrosinase inhibitors as anti-melanogenic agents: Design, synthesis, structural …

L Ielo, B Deri, MP Germano, S Vittorio, S Mirabile… - European journal of …, 2019 - Elsevier
… no considerable cytotoxicity and showed anti-melanogenic effects on B16F10 melanoma …
further structural modification of this class of compounds as future anti-melanogenic agents. …

Melanogenesis inhibitors

S Kumari, STG Thng, NK Verma, HK Gautam - 2018 - dr.ntu.edu.sg
… compounds with potential anti-melanogenic activities (4). … as a chelating agent for Cu2+
in the active site of tyrosinase. In … Besides the natural sources, tyrosinase inhibitors are also …

[HTML][HTML] Tyrosinase-based TLC autography for anti-melanogenic drug screening

KD Hsu, YH Chan, HJ Chen, SP Lin, KC Cheng - Scientific Reports, 2018 - nature.com
… , the discovery of novel tyrosinase inhibitors for the development of anti-melanogenic drug
has … was employed to develop a tyrosinase-based TLC for anti-melanogenic drugs screening. …

A novel anti-melanogenic agent, KDZ-001, inhibits tyrosinase enzymatic activity

KS Hwang, JY Yang, J Lee, YR Lee, SS Kim… - Journal of …, 2018 - Elsevier
… In this study, we show that KDZ-001, a novel anti-melanogenic agent, strongly inhibits
inhibits TYR enzymatic activity. Thus, KDZ-001 is a potential candidate for a skin-whitening agent