Proanthocyanidins Extracted from Rhododendron pulchrum Leaves as Source of Tyrosinase Inhibitors: Structure, Activity, and Mechanism

WM Chai, R Wang, MK Wei, ZR Zou, RG Deng, WS Liu… - PloS one, 2015 - journals.plos.org
… -tyrosinase activity, and mechanism of proanthocyanidins extracted from Rhododendron
pulchrum … The anti-tyrosinase analysis results indicated that the mixtures were reversible and …

Natural and bioinspired phenolic compounds as tyrosinase inhibitors for the treatment of skin hyperpigmentation: Recent advances

L Panzella, A Napolitano - Cosmetics, 2019 - mdpi.com
inhibition of tyrosinase, a copper-containing enzyme which catalyzes the key steps of
melanogenesis. This review focuses on the tyrosinase inhibition … human tyrosinase inhibitors have …

Valonea tannin: Tyrosinase inhibition activity, structural elucidation and insights into the inhibition mechanism

J Liu, Y Liu, X He, B Teng, JM McRae - Molecules, 2021 - mdpi.com
… This study investigated the tyrosinase inhibition activity of … Tyrosinase inhibition assays
demonstrated that valonea tannin … Kinetic studies of the inhibition reactions indicated that …

[HTML][HTML] Research progress on the identification and pharmacological activity of the active compo-nents of the rhododendron species

MH Han, KY Kim - Biosciences Biotechnology Research Asia, 2021 - biotech-asia.org
… activity and mechanism of proanthocyanidins obtained from Rhododendrontyrosinase
analysis of the above compounds show reversible and mixed competitive tyrosinase inhibitors

Natural tyrosinase enzyme inhibitors: A path from melanin to melanoma and its reported pharmacological activities

R Logesh, SR Prasad, S Chipurupalli… - … et Biophysica Acta (BBA …, 2023 - Elsevier
… The production of melanin pigment is dependent on tyrosine levels. L-tyrosine and L-dihydroxyphenylalanine
(L-DOPA) can serve both as a substrates and intermediates of melanin …

Anti-tyrosinase and antioxidant activity of proanthocyanidins from Cinnamomum camphora

H Yang, P Xu, W Song, X Zhai - International Journal of Food …, 2021 - Taylor & Francis
… [Citation1] Melanin production can be controlled by controlling the activity of tyrosinase;
thus, tyrosinase inhibitors have been highly applied into beauty and whitening, health care, …

Hop tannins as multifunctional tyrosinase inhibitor: Structure characterization, inhibition activity, and mechanism

J Liu, Y Chen, X Zhang, J Zheng, W Hu, B Teng - Antioxidants, 2022 - mdpi.com
… In the shorter conference version of this research, we found that hop tannins showed
tyrosinase inhibition ability, and preliminarily observed the tyrosinase–tannin interaction with …

Rifampicin as a novel tyrosinase inhibitor: Inhibitory activity and mechanism

WM Chai, MZ Lin, FJ Song, YX Wang, KL Xu… - International journal of …, 2017 - Elsevier
… This work identified a novel tyrosinase inhibitor and potentially contributed to the usage of
… its efficient inhibition. Therefore, this study confirmed a new and efficient tyrosinase inhibitor, …

Integrative Metabolomic and Transcriptomic Analysis Unveils the Formation Mechanism of Crimson Basal Blotches in the Petals of Rhododendron Rex

SQ Wang, XL Zhou, L Yang, ZY Lyu, R Zhang… - Available at SSRN … - papers.ssrn.com
… variations of flower color, the corolla in many Rhododendron … of Rhododendron largely
concentrated in overall corolla color… flavonoid biosynthesis regulation in Rhododendron pulchrum

Transcriptome and Flavonoid Compounds Metabolome Analyses Reveal the Mechanisms of Heat Stress in Rhododendron with Exogenously Applied Calcium

J Shen, X Rong, X Li, Y Ma, H Cheng, J Sheng… - Agronomy, 2024 - mdpi.com
… This study explores the mechanism by which exogenous calcium alleviates heat stress
and the role of flavonoids in regulating the antioxidative system in Rhododendron × pulchrum