… Tyrosine hydroxylase is the rate-limiting enzyme of catecholamine biosynthesis; it uses
tetrahydrobiopterin and molecular oxygen to convert tyrosine to DOPA. Its amino terminal 150 …

… Tyrosine hydroxylase deficiency has been reported in … tyrosine hydroxylase deficiency and
reviewed the literature. Based on the presenting neurological features, tyrosine hydroxylase …

… Reports of the enzymatic conversion of tyrosine to catecholamines by tissue slices and
minces have generally been unconvincing owing to large and variable blanks with boiled …

… Tyrosine hydroxylase (TH) catalyzes the conversion of l-tyrosine to l-dopa, which is the
initial and rate-limiting step in the biosynthesis of catecholamines [CA; dopamine (DA), …

… tyrosine hydroxylase catalysed reaction as the rate-limiting step in the normal catecholamine
biosynthesis … catecholamine biosynthesis other enzymes in the pathway may become rate-…

… catecholamine synthesis in the brain and peripheral cells that normally synthesize
catecholamines … tyrosinase is used for catecholamine synthesis under normal circumstances, as …

… Given the growing literature suggesting that different tissues regulate tyrosine hydroxylase
… in the control of catecholamine biosynthesis. Key Words: Tyrosine hydroxylase—Gene …

… Tyrosine hydroxylase degradation by the ubiquitin–… tyrosine hydroxylase expression and
activity and highlight their physiological importance in the control of catecholamine biosynthesis…

… IT IS well established that tyrosine hydroxylase (TH) activity is regulated in response to
the demand for catecholamines (CAs). The synthesis of the enzyme is increased in the adrenal …

… Depolarizing stimuli increase catecholamine (CA) biosynthesis, tyrosine hydroxylase (TH) …
Tyrosine hydroxylase (TH) is the rate-limiting enzyme in catecholamine (CA) biosynthesis. …