Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG)

S Popat, TC Hsia, JY Hung, HA Jung, JY Shih… - The …, 2022 - academic.oup.com
Background Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are
standard of care for patients with EGFR mutation-positive non–small-cell lung cancer (NSCLC) …

EGFR tyrosine kinase inhibitor therapy for lung cancer treatments and their clinical outcomes: A cohort study in Taiwan

CH Chung - Oncology Letters, 2019 - spandidos-publications.com
… Prior to the development of epidermal growth factor receptor (EGFR)-tyrosine kinase
inhibitor (TKI) … The aim of the present retrospective cohort study was to determine the real-world …

Tyrosine Kinase Inhibitors and Vascular Adverse Events in Patients with Chronic Myeloid Leukemia: A Population-Based, Propensity Score-Matched Cohort Study

MT Chen, ST Huang, CW Lin, BS Ko, WJ Chen… - The …, 2021 - academic.oup.com
… To reduce the selection bias inherent to retrospective cohort studies, we conducted
propensity score matching to control for potential confounders [34]. Baseline characteristics, …

[HTML][HTML] Tyrosine kinase inhibitors significantly improved survival outcomes in patients with metastatic gastrointestinal stromal tumour: a multi-institutional cohort study

AD Tan, K Willemsma, A MacNeill, K DeVries… - Current …, 2020 - ncbi.nlm.nih.gov
Study Design In a retrospective cohort study, we assessed the effect of tki availability on
outcomes in patients diagnosed with metastatic gist in British Columbia between 1996 and 2016…

… growth factor receptor mutated non-small cell lung cancer using different tyrosine kinase inhibitors in The Netherlands: a retrospective, nationwide registry study

RGP Gijtenbeek, RAM Damhuis… - The Lancet Regional …, 2023 - thelancet.com
… To our knowledge, this is one of the largest cohort studies from Western Europe reporting
real-world treatment effects of first-, second- and third-generation TKI, stratifying between …

[HTML][HTML] … clinical outcomes of first-generation and second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large cohort of European non …

A Pluzanski, M Krzakowski, D Kowalski… - ESMO open, 2020 - Elsevier
… factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) are … exists on efficacy of EGFR TKIs
in European patient cohorts. … from eight randomised studies and 82 cohort studies (HR 0.99…

[HTML][HTML] Fatigue in chronic myeloid leukemia patients on tyrosine kinase inhibitor therapy: predictors and the relationship with physical activity

L Janssen, NMA Blijlevens, MMCM Drissen… - …, 2021 - ncbi.nlm.nih.gov
… Fatigue is a common side effect of tyrosine kinase inhibitor (TKI) therapy in patients with …
of fatigue and its relationship with physical activity. In this study, 220 CML patients receiving TKI …

Plasma concentrations of tyrosine kinase inhibitors imatinib, erlotinib, and sunitinib in routine clinical outpatient cancer care

NAG Lankheet, LM Knapen… - Therapeutic drug …, 2014 - journals.lww.com
… The objectives of this study were to evaluate the plasma concentrations of the tyrosine
kinase inhibitors (TKIs), imatinib, erlotinib, and sunitinib, in a cohort of patients with cancer in …

… of paediatric patients with B-cell acute lymphocytic leukaemia with ABL-class fusion in the pre-tyrosine-kinase inhibitor era: a multicentre, retrospective, cohort study

ML den Boer, G Cario, AV Moorman, JM Boer… - The Lancet …, 2021 - thelancet.com
… The results described in this study will serve as reference to interpret the potential benefit
of adding tyrosine-kinase inhibitors to the first-line treatment regimens of children with ABL-…

Impact of the treatment of chronic myeloid leukaemia by tyrosine-kinase inhibitors on sick leaves refund: a nationwide cohort study

C Conte, F Vayr, MC Pajiep, F Despas, F Huguet… - Supportive Care in …, 2022 - Springer
… of BCR-ABL tyrosine kinase inhibitors (TKI), … studies suggest a significant impact of
haematologic malignancies and their treatment on patients’ employment. A Danish cohort study of …