Nationwide real-world cohort study of first-line tyrosine kinase inhibitor treatment in epidermal growth factor receptor-mutated non–small-cell lung cancer

RGP Gijtenbeek, RAM Damhuis, HJM Groen… - Clinical lung cancer, 2020 - Elsevier
… trials directly compared the relative efficacy of tyrosine kinase inhibitors (TKIs) in patients with
… Therefore, the aim of this study was to assess the overall survival (OS) of advanced EGFR-…

[HTML][HTML] EGFR tyrosine kinase inhibitor therapy for lung cancer treatments and their clinical outcomes: A cohort study in Taiwan

CH Chung - Oncology Letters, 2019 - spandidos-publications.com
… A better suited drug treatment may be associated with improved outcomes. The aim of …
cohort study was to determine the real-world prescription rates of the various drugs used to treat

Cardiovascular events associated with use of tyrosine kinase inhibitors in chronic myeloid leukemia: a population-based cohort study

T Dahlén, G Edgren, M Lambe, M Höglund… - Annals of internal …, 2016 - acpjournals.org
Study Design Among the population of patients with CML, we conducted a retrospective
cohort study … chronic phase who were receiving TKI treatment. All patients were followed from …

Prognostic factors and survival outcomes in patients with chronic myeloid leukemia in blast phase in the tyrosine kinase inhibitor era: Cohort study of 477 patients

P Jain, HM Kantarjian, A Ghorab, K Sasaki… - Cancer, 2017 - Wiley Online Library
… With the widespread use of tyrosine kinase inhibitors (TKIs) for the treatment of patients with
chronic myeloid leukemia (CML), the risk of transformation to blast phase (BP) has markedly …

Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG)

S Popat, TC Hsia, JY Hung, HA Jung, JY Shih… - The …, 2022 - academic.oup.com
… Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKIs) are standard of care
for patients with EGFR mutation-positive non–small-cell lung cancer (NSCLC) with common …

Tyrosine Kinase Inhibitors and Vascular Adverse Events in Patients with Chronic Myeloid Leukemia: A Population-Based, Propensity Score-Matched Cohort Study

MT Chen, ST Huang, CW Lin, BS Ko, WJ Chen… - The …, 2021 - academic.oup.com
… To reduce the selection bias inherent to retrospective cohort studies, we conducted
propensity score matching to control for potential confounders [34]. Baseline characteristics, …

[HTML][HTML] … inhibitor and tyrosine kinase inhibitor combination therapy for advanced or metastatic renal cell carcinoma: A multicenter retrospective real-world cohort study

K Iinuma, T Yamada, K Kameyama, T Taniguchi… - Cancers, 2023 - mdpi.com
… of immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKI) (ICI+TKI) in 51
patients with advanced or metastatic renal cell carcinoma (mRCC). In this study, 7.0 months …

First-or second-generation epidermal growth factor receptor tyrosine kinase inhibitors in a large, real-world cohort of patients with non-small cell lung cancer

ACC Huang, CH Huang, JS Ju… - Therapeutic …, 2021 - journals.sagepub.com
… -world cohorts of Asian patients with NSCLC. The present study aimed to analyze the treatment
efficacy of EGFR-TKIs and acquired T790M resistance in a large cohort of Asian patients …

Treatment outcomes of non-small cell lung cancers treated with EGFR tyrosine kinase inhibitors: a real-world cohort study

O Manninen, L Puuniemi, S Iivanainen, M Arffman… - Acta …, 2023 - Taylor & Francis
study, we investigated the use of EGFR TKIs and treatment outcomes in RWE settings using
a large nationwide cohort… for afatinib than gefitinib treated patients which was presumably …

[HTML][HTML] … factor receptor mutated non-small cell lung cancer using different tyrosine kinase inhibitors in The Netherlands: a retrospective, nationwide registry study

RGP Gijtenbeek, RAM Damhuis… - The Lancet Regional …, 2023 - thelancet.com
… % of patients received brain imaging before treatment start. To our knowledge, this is one of
the largest cohort studies from Western Europe reporting real-world treatment effects of first-, …