Tyrosine kinase inhibitors in cancer therapy
S Madhusudan, TS Ganesan - Clinical biochemistry, 2004 - Elsevier
… have emerged as a new promising target for cancer therapy. This review will … of tyrosine
kinases in cancer and the development of specific tyrosine kinase blockers for cancer therapy …
kinases in cancer and the development of specific tyrosine kinase blockers for cancer therapy …
Role of tyrosine kinase inhibitors in cancer therapy
A Arora, EM Scholar - … of Pharmacology and Experimental Therapeutics, 2005 - ASPET
… types of targeted therapy are available, but this review focuses in particular only on small
molecule tyrosine kinase inhibitors. Three have been approved for use in cancer therapy, and …
molecule tyrosine kinase inhibitors. Three have been approved for use in cancer therapy, and …
[HTML][HTML] Smart drugs: tyrosine kinase inhibitors in cancer therapy
LK Shawver, D Slamon, A Ullrich - Cancer cell, 2002 - cell.com
… ), the p210 Bcr-Abl is a constitutively active cytoplasmic tyrosine kinase present in virtually
all … It is a model target for cancer therapy, because the Bcr-Abl tyrosine kinase by itself is …
all … It is a model target for cancer therapy, because the Bcr-Abl tyrosine kinase by itself is …
Recent advances on anti-angiogenesis receptor tyrosine kinase inhibitors in cancer therapy
S Qin, A Li, M Yi, S Yu, M Zhang, K Wu - Journal of hematology & oncology, 2019 - Springer
… and regarded as attractive therapeutic candidates. By April 2017, among the 35 protein
kinase inhibitors (PKIs) approved, 31 are used in cancer therapy [14]. For example, sorafenib, …
kinase inhibitors (PKIs) approved, 31 are used in cancer therapy [14]. For example, sorafenib, …
Protein tyrosine kinase inhibitors in cancer treatment
PM Traxler - Expert Opinion on Therapeutic Patents, 1997 - Taylor & Francis
… of tyrosine kinase inhibitors has increased in the last few years. New receptor and non-receptor
tyrosine kinases … -receptor (EGFR) tyrosine kinase has been developed and successfully …
tyrosine kinases … -receptor (EGFR) tyrosine kinase has been developed and successfully …
A comprehensive review of protein kinase inhibitors for cancer therapy
R Kannaiyan, D Mahadevan - Expert review of anticancer therapy, 2018 - Taylor & Francis
… Several protein kinase inhibitors have been approved by FDA in the last few decades. …
protein kinase inhibitors as of December 2017 for the well-known oncogenic protein kinases. A list …
protein kinase inhibitors as of December 2017 for the well-known oncogenic protein kinases. A list …
Tyrosine kinase inhibitors in cancer treatment (part II)
P Traxler - Expert Opinion on Therapeutic Patents, 1998 - Taylor & Francis
… of inhibitors in the ATP-binding site of protein kinases have … design of tyrosine as well as
serine/threonine kinase inhibitors. It has … of protein kinases is an exciting target for the design of …
serine/threonine kinase inhibitors. It has … of protein kinases is an exciting target for the design of …
Acquired resistance to tyrosine kinase inhibitors during cancer therapy
JA Engelman, J Settleman - Current opinion in genetics & development, 2008 - Elsevier
… tyrosine kinase inhibitors have emerged as important therapeutic agents in the treatment
of … The recent development of several selective TKIs for cancer therapy has already had a …
of … The recent development of several selective TKIs for cancer therapy has already had a …
Tyrosine kinase blockers: new hope for successful cancer therapy
D Pytel, T Sliwinski, T Poplawski… - Anti-Cancer Agents …, 2009 - ingentaconnect.com
… of new drugs with tyrosine kinase blockers for cancer treatment. … tyrosine kinases blockers
effective in cancer treatment. Future treatment regiments are likely to include multiple tyrosine …
effective in cancer treatment. Future treatment regiments are likely to include multiple tyrosine …
[PDF][PDF] Emerging roles of targeted small molecule protein-tyrosine kinase inhibitors in cancer therapy
JK Smith, NM Mamoon, RJ Duhé - … Clinical Cancer Therapeutics, 2003 - researchgate.net
… treatment with high concen- discussion of recombinant monoclonal antibody cancer therapy
… use of low molecular weight tyrosine kinase inhibitors, which were capable of competitively …
… use of low molecular weight tyrosine kinase inhibitors, which were capable of competitively …
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