Pien Tze Huang accelerated wound healing by inhibition of abnormal fibroblast apoptosis in Streptozotocin induced diabetic mice

Y Yan, X Liu, Y Zhuang, Y Zhai, X Yang, Y Yang… - Journal of …, 2020 - Elsevier
… which PZH promoted the wound healing was also discussed. … Local used PZH improves
wound healing by inhibiting the … of a topical dosage form of PZH for diabetic wound healing. …

Intragastric administration of Pien Tze Huang enhanced wound healing in diabetes by inhibiting inflammation and improving energy generation

J Zhang, G Cao, L Tian, J Hou, Y Zhang, H Xu, M Wang… - Phytomedicine, 2023 - Elsevier
… role of inflammation and energy generation in diabetic wound healing, reveals wound
repair mechanism of PZH and promotes its clinical application in diabetic wound treatment. …

Pien-tze-huang promotes wound healing in streptozotocin-induced diabetes models associated with improving oxidative stress via the Nrf2/ARE pathway

Y Liu, J Mo, F Liang, S Jiang, J Xiong… - Frontiers in …, 2023 - frontiersin.org
… In conclusion, the positive role of PZH in diabetic wound healing might be related to the
activation of the Nrf2/ARE pathway to regulate the level of oxidative stress in vivo and increase …

Integrating RNA-sequencing and network analysis to explore the mechanism of topical Pien Tze Huang treatment on diabetic wounds

GZ Cao, LL Tian, JY Hou, Y Zhang, H Xu… - Frontiers in …, 2024 - frontiersin.org
Wound healing was assessed by wound closure rate, two-… that PZH significantly accelerated
wound healing, as well as … role in diabetic wound healing, including Notoginsenoside R1, …

Pien Tze Huang Inhibits Hypoxia‐Induced Angiogenesis via HIF‐1α/VEGF‐A Pathway in Colorectal Cancer

H Chen, J Feng, Y Zhang, A Shen… - Evidence‐Based …, 2015 - Wiley Online Library
… demonstrating the effects of Pien Tze Huang (PZH) on vascularization in the normal injured
tissue, PZH is believed to be able to promote would healing because it has long been used …

[HTML][HTML] Pien Tze Huang inhibits metastasis of human colorectal carcinoma cells via modulation of TGF-β1/ZEB/miR‑200 signaling network

A Shen, W Lin, Y Chen, L Liu… - International …, 2015 - spandidos-publications.com
… Using wound healing and transwell assays we found that PZH treatment significantly
inhibited the migration and invasion of human colorectal carcinoma HCT-8 cells in a dose-…

Pien Tze Huang suppresses VEGF-C-mediated lymphangiogenesis in colorectal cancer

J Lin, J Feng, Y Jin, Z Yan, Z Lai… - Oncology …, 2016 - spandidos-publications.com
… The images of wound healing are representative images of three independent experiments,
… One such prescription is Pien Tze Huang (PZH), which exhibits specific anticancer activities. …

A dipeptidyl peptidase‐4 inhibitor promotes wound healing in normoglycemic mice by modulating keratinocyte activity

CM Shih, CY Huang, CY Huang… - Experimental …, 2018 - Wiley Online Library
… study was to evaluate the role of a DPP-4 inhibitor in experimental wound-healing pathogenesis
and to identify novel medications as potential treatments that promote wound healing. …

Pien-Tze-Huang ameliorates hepatic fibrosis via suppressing NF-κB pathway and promoting HSC apoptosis

H Zheng, X Wang, Y Zhang, L Chen, L Hua… - Journal of …, 2019 - Elsevier
Ethnopharmacological relevance Pien Tze Huang (PZH), a Chinese herbal formula, has
various forms of pharmacological activity including anti-inflammation, liver protection and anti-…

[HTML][HTML] Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathways

A Shen, J Lin, Y Chen, W Lin, L Liu… - Oncology …, 2013 - spandidos-publications.com
… Angiogenesis, the formation of new blood vessels from the pre-existing vasculatures,
plays an important role in a wide range of biological processes including wound healing, …