… In this study, 133 unrelated Chinese women with familial breast/ovarian cancer living in
Zhejiang, eastern China, were enrolled between the years 2008 and 2014. The complete coding …

… Breast cancer is the most common cancer among Chinese women, with 260,000 new … ,
and 30% of both BRCA1 and BRCA2 variants remained as unclassified variants (Fig. 1 a). This …

… elevated carrier frequencies in specific variants that confer milder disease. For instance,
we detected a predominant GJB2 variant among Chinese and Malays; c.109G > A (p.Val37Ile; …

… ), with 13 carrying BRCA1 and 30 carrying BRCA2 variants. Based on these data, we …
variant out of every 265 Chinese Han individuals, and 5.1 million carriers among the Chinese …

… Nowadays, breast cancer is the most common cancer among Chinese women, with …
Interestingly, 333 out of 400 inconsistent categorized variants were marked as “unclassified” in …

… variants, we tested the Unclassified variants (online supplemental table S8). We selected the
Unclassified variants … based studies conducted among Chinese women. Breast Cancer Res …

… , squamous cell carcinoma patients, and patients with unclassified types of pathologies; the
… than 49 years, menopausal women, and women who had experienced vaginal pregnancies. …

… in Chinese, 19 263 in Korean and 37 432 in Japanese. We extracted all BRCA variants from
… total of 3222 distinct BRCA variants including 518 in Indian, 1524 in Chinese, 581 in Korean …

… China and observed a 20.2% overall pathogenic variant frequency for BRCA1/2 genes. MLPA
assay on the patients lacking small pathogenic variants … /2 pathogenic variant frequency to …

… Southern Chinese population were based on women with … only in Southern Chinese population
and not Northern Chinese … the Northern and Southern Chinese populations [44]. Hence, …