A comprehensive review of uncommon EGFR mutations in patients with non-small cell lung cancer

HY Tu, EE Ke, JJ Yang, YL Sun, HH Yan, MY Zheng… - Lung Cancer, 2017 - Elsevier
… This study reviewed the prevalence of uncommon EGFR mutations and their sensitivity to
EGFR… L858R mutations, indicating that they may benefit from EGFR-TKIs as a first-line therapy. …

Uncommon EGFR mutations in advanced non-small cell lung cancer

GM O'Kane, PA Bradbury, R Feld, NB Leighl, G Liu… - Lung Cancer, 2017 - Elsevier
… incidence of uncommon EGFR mutations and summarizes reported outcomes when treated
with EGFR-TKIs. … Exon 20 insertions in EGFR are the most prevalent of the uncommon EGFR

[HTML][HTML] Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

T Zhang, B Wan, Y Zhao, C Li, H Liu, T Lv… - … lung cancer research, 2019 - ncbi.nlm.nih.gov
… of uncommon EGFR mutations. The treatment for patients with NSCLC … uncommon EGFR
mutations remains a subject of debate and the sensitivity of uncommon EGFR mutations to …

[HTML][HTML] … responses to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with uncommon EGFR mutations: new insights and future …

A Russo, T Franchina, G Ricciardi, A Battaglia… - International Journal of …, 2019 - mdpi.com
… NSCLC, but its role in patients harboring EGFR mutations … of uncommon mutations to
currently available EGFR TKIs is … patients harboring uncommon EGFR mutations with currently …

[HTML][HTML] Uncommon EGFR Compound Mutations in Non-Small Cell Lung Cancer (NSCLC): A Systematic Review of Available Evidence

I Attili, A Passaro, P Pisapia, U Malapelle… - Current Oncology, 2022 - mdpi.com
… cases involve other mutation sites within or, … uncommon EGFR mutations (incidence ≤ 5%
each). Evidence on the efficacy of EGFR TKIs in NSCLC patients harboring uncommon EGFR

[HTML][HTML] Uncommon EGFR mutations in lung adenocarcinoma: features and response to tyrosine kinase inhibitors

A Brindel, W Althakfi, M Barritault, E Watkin… - Journal of Thoracic …, 2020 - ncbi.nlm.nih.gov
… In conclusion, uncommon EGFR mutations may be associated with a poor outcome and the
… in cases of double uncommon mutations and such patients should be treated accordingly. …

[HTML][HTML] Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors in non-small cell lung cancer harboring uncommon EGFR mutations: Focus on afatinib

A Masood, RK Kancha, J Subramanian - Seminars in oncology, 2019 - Elsevier
mutations in the EGFR. However, limited data are available regarding the activity of available
EGFR TKIs against uncommon EGFR mutations. … of patients with uncommon mutations for …

[HTML][HTML] Uncommon EGFR mutations in non-small-cell lung cancer: A systematic literature review of prevalence and clinical outcomes

T John, A Taylor, H Wang, C Eichinger, C Freeman… - Cancer …, 2022 - Elsevier
… “uncommonmutations. We conducted a systematic literature review to identify evidence
on uncommon EGFR mutations … /metastatic NSCLC and uncommon EGFR mutations (excluding …

EGFR tyrosine kinase inhibitor (TKI) in patients with advanced non-small cell lung cancer (NSCLC) harboring uncommon EGFR mutations: A real-world study in China

J Xu, B Jin, T Chu, X Dong, H Yang, Y Zhang, D Wu… - Lung cancer, 2016 - Elsevier
… of patients with multiple uncommon EGFR mutations and their sensitivity to EGFR TKIs. … of
EGFR TKIs in patients with uncommon EGFR mutations, which were defined as any mutation

Uncommon EGFR mutations associate with lower incidence of T790M mutation after EGFR-TKI treatment in patients with advanced NSCLC

S Yang, S Mao, X Li, C Zhao, Q Liu, X Yu, Y Wang… - Lung Cancer, 2020 - Elsevier
… ) mutations have stepped into the era of targeted therapy. … mutation and their outcome to
subsequent osimertinib in patients of advanced NSCLC harboring uncommon EGFR mutations. …