[HTML][HTML] Underlying causes and therapeutic targeting of the inflammatory tumor microenvironment

EA Comen, RL Bowman, M Kleppe - Frontiers in cell and …, 2018 - frontiersin.org
… of tumor suppressors. In this review, we examine the concept of the tumor microenvironment
as … in an inflammatory response and the tumor microenvironment may shed light on new …

[HTML][HTML] Tumor microenvironment

B Arneth - Medicina, 2019 - mdpi.com
Background and Objectives: The tumor microenvironment has been widely implicated in
tumorigenesis because it harbors tumor cells that interact with surrounding cells through the …

[HTML][HTML] Underlying mechanisms and drug intervention strategies for the tumour microenvironment

H Li, L Zhou, J Zhou, Q Li, Q Ji - Journal of Experimental & Clinical Cancer …, 2021 - Springer
… Cancer occurs in a complex tissue environment, and its progression depends largely on
the tumour microenvironment (TME). The TME has a highly complex and comprehensive …

[HTML][HTML] The mechanism underlying the ncRNA dysregulation pattern in hepatocellular carcinoma and its tumor microenvironment

C Xue, X Gu, Z Bao, Y Su, J Lu, L Li - Frontiers in immunology, 2022 - frontiersin.org
tumor microenvironment (TME). In this review, we summarized the aberrant epigenetic and
genetic alterations that cause … role of ncRNAs in regulating tumor-associated macrophages (…

Tumor microenvironment and progression

HF Dvorak, VM Weaver, TD Tlsty… - Journal of surgical …, 2011 - Wiley Online Library
Tumor blood vessels are heterogeneous, of at least six distinct types, are induced primarily
by vascular endothelial growth factor‐A (VEGF‐A), and provide a potentially useful …

The acidic tumor microenvironment as a driver of cancer

E Boedtkjer, SF Pedersen - Annual review of physiology, 2020 - annualreviews.org
… , the compartmentalized pH microenvironment favors cancer … the acidity of the tumor
microenvironment influences each stage … The underlying signaling mechanisms responsible for …

[HTML][HTML] The role of tumor microenvironment in cancer metastasis: Molecular mechanisms and therapeutic opportunities

CM Neophytou, M Panagi, T Stylianopoulos… - Cancers, 2021 - mdpi.com
… The tumor microenvironment (TME) regulates essential tumor survival and promotion
functions. Interactions between the cellular and structural components of the TME allow cancer …

Tumormicroenvironment interactions: Dangerous liaisons

IP Witz - Advances in cancer research, 2008 - Elsevier
… The molecular pathways underlying the heterogeneity of tumors are very complex. Genetic,
… occurring at the tumor microenvironment, we noticed that several tumor types propagating in …

Understanding the tumor microenvironment for effective immunotherapy

H Sadeghi Rad, J Monkman… - Medicinal research …, 2021 - Wiley Online Library
… level, and in the context of their tumor microenvironment (TME) is becoming increasingly …
of tumor and immune cells. The immune landscape of the TME can inhibit or promote tumor

Tumor microenvironment components: Allies of cancer progression

PIR Franco, AP Rodrigues, LB de Menezes… - … -Research and Practice, 2020 - Elsevier
tumor microenvironment and induce angiogenesis have important roles in the onset and
progression of the tumor… , which modulate tumor cells and the tumor microenvironment to favor …