Management of undifferentiated thyroid cancer

KB Ain - Best Practice & Research Clinical Endocrinology & …, 2000 - Elsevier
… The extreme of undifferentiated clinical behaviour is epitomized by anaplastic thyroid
carcinoma, a rare, terminally dedifferentiated malignancy that is rapidly and invariably fatal. It is …

Anaplastic (undifferentiated) thyroid cancer: improved insight and therapeutic strategy into a highly aggressive disease

JP O'neill, B O'Neill, C Condron, M Walsh… - The Journal of …, 2005 - cambridge.org
… Background: This review article discusses the clinical and diagnostic implications of anaplastic
thyroid cancer, recognizing the aggressive nature of the disease and extensive disease …

Thyroid cancer review 3: management of medullary and undifferentiated thyroid cancer

PA Nix, A Nicolaides… - International journal of …, 2006 - Wiley Online Library
… on thyroid cancer. This article will deal with the rare forms of thyroid cancer which comprise
medullary thyroid cancer … , anaplastic carcinoma, thyroid lymphoma and squamous cell …

Thyroid cancer

O Gimm - Cancer letters, 2001 - Elsevier
… carcinoma (PTC) may have a very benign course while undifferentiated thyroid carcinoma
(UTC) belongs to the most aggressive human malignancies. A variety of genes have been …

[PDF][PDF] Poorly differentiated and undifferentiated thyroid carcinomas

M SobRinho-SiMõES - Turk Patoloji Dergisi, 2015 - researchgate.net
Thyroid cancer is the most common endocrine malignancy and its incidence goes on …
Undifferentiated thyroid carcinoma (UTC) corresponds to the most aggressive form of thyroid cancer

Update on fundamental mechanisms of thyroid cancer

A Prete, P Borges de Souza, S Censi… - Frontiers in …, 2020 - frontiersin.org
… The molecular pathogenesis of thyroid cancer involves dysregulation of the mitogen-… ,
and activating mutations in TERT promoter are frequent in undifferentiated thyroid cancer. …

Genetic alterations in poorly differentiated and undifferentiated thyroid carcinomas

P Soares, J Lima, A Preto, P Castro, J Vinagre… - Current …, 2011 - ingentaconnect.com
… with silencing of iodinetransporting genes in thyroid cancer indicates that targeting BRAF
may contribute for improving the iodine uptake ability of thyroid cancer cells [21, 23, 25]. …

Biological role and potential therapeutic targeting of the chemokine receptor CXCR4 in undifferentiated thyroid cancer

V De Falco, V Guarino, E Avilla, MD Castellone… - Cancer research, 2007 - AACR
Anaplastic thyroid carcinoma (ATC) is a rare thyroid cancer type with an extremely poor
prognosis. Despite appropriate treatment, which includes surgery, radiotherapy, and …

An evidence-based review of poorly differentiated thyroid cancer

EMS Jr, VA LiVolsi, J Brierley, J Shin… - World journal of …, 2007 - Springer
… Some subset of patients with PDTC may be misdiagnosed with undifferentiated tumors. If …
2%–3% of thyroid cancer patients in North America (but up to 15% of thyroid cancer patients in …

High efficacy of concomitant treatment of undifferentiated (anaplastic) thyroid cancer with radiation and docetaxel

M Troch, O Koperek, C Scheuba… - The Journal of …, 2010 - academic.oup.com
Context: Anaplastic thyroid carcinoma (ATC) is a rare but aggressive solid tumor with a very
short survival time even with multimodality treatment. In view of in vitro data and the high rate …