… caused 228 million clinical episodes, 2–4 million of which were severe malaria cases, and
… key components of the so called pathological triumvirate which leads to severe malaria (SM). …

… , leading to various connected disorders to severe malaria. Very high cytokine levels have
been reported to elicit the following pathophysiology, namely a reduction in the utilization of …

… the pathophysiology of severe malaria and treatment recommendations for severe disease
… is due primarily to clinical syndromes of cerebral malaria, severe malarial anemia (SMA), and …

… The sole purpose of the present article was to give an overview of pathological outcomes
during severe malaria along with their molecular mechanisms. A large proportion of deaths …

… In addition, updates in other severe falciparum and non-falciparum … in severe malaria
pathogenesis, with a specific focus on new pathogenetic mechanisms leading to cerebral malaria. …

… cytokines in particular, in severe falciparum malaria in adults is not well … To determine the
prognostic and pathophysiologic … in a large series of Vietnamese adults with severe malaria. …

… This review summarizes progress in preventing and treating severe malaria, which has
been accompanied by advances in our understanding of the pathogenesis of severe malaria …

… malaria cases (range 1–38%) [9]. The case fatality rate in returning travelers with falciparum
malaria varies from 0.6% to 3.8%, and for severe malaria it … updated information on malaria …

… All patients with confirmed severe malaria should receive … first-line treatment for severe
malaria. Randamozied controlled … , and therefore its use in severe malaria should be avoided. …

… Acute renal failure in severe malaria is defined by creatinine > 3 mg/dL or blood urea nitrogen
> 56 mg/dL [45••]. Severe malaria promotes renal damage by affecting different structures …