[HTML][HTML] Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial

RS Herbst, P Baas, JL Perez-Gracia, E Felip, DW Kim… - Annals of …, 2019 - Elsevier
… -1 protein (PD)-L1-positive advanced non-… analysis compared outcomes in patients based
on PD-L1 expression in archival versus newly collected tumor samples using recently updated

Updated analysis of KEYNOTE-024: pembrolizumab versus platinum-based chemotherapy for advanced non–small-cell lung cancer with PD-L1 tumor proportion …

M Reck, D Rodríguez–Abreu, AG Robinson… - Journal of Clinical …, 2019 - ascopubs.org
… We report an updated analysis of OS and other efficacy and safety outcomes after a median
follow-up of 25.2 months. In addition, we describe outcomes among patients who crossed …

Pembrolizumab in patients (pts) with PD-L1–positive (PD-L1+) advanced ovarian cancer: Updated analysis of KEYNOTE-028.

A Varga, SA Piha-Paul, PA Ott, JM Mehnert… - 2017 - ascopubs.org
… ) suggested that the PD-1 inhibitor pembrolizumab has promising antitumor activity in pts
with PD-L1 + advanced ovarian cancer. An updated analysis of the ovarian cancer cohort …

Prognostic significance of PD-L1 in solid tumor: an updated meta-analysis

Q Wang, F Liu, L Liu - Medicine, 2017 - journals.lww.com
… However, whether PD-L1 expression is a prognostic factor for … role of PD-L1 expression
through a meta-analysis update of … -analysis suggest the correlation of PD-L1 overexpression …

PD-L1 expression as a predictive biomarker in advanced non-small-cell lung cancer: updated survival data

PN Aguiar Jr, RA De Mello, P Hall, H Tadokoro… - …, 2017 - Taylor & Francis
… is PD-L1 expression, its clinical significance is still debatable. In this article, we show the
updated survival analysis … study update is to assess the survival according to PD-L1 expression. …

Updated overall survival and PD-L1 subgroup analysis of patients with extensive-stage small-cell lung cancer treated with atezolizumab, carboplatin, and etoposide …

SV Liu, M Reck, AS Mansfield, T Mok… - Journal of Clinical …, 2021 - ascopubs.org
… preplanned updated OS analysisUpdated analyses of safety and OS by blood-based tumor
mutational burden (bTMB) levels, as well as exploratory analyses of OS according to PD-L1

OA 17.06 updated analysis of KEYNOTE-024: pembrolizumab vs platinum-based chemotherapy for advanced NSCLC with PD-L1 TPS≥ 50%

J Brahmer, D Rodríguez-Abreu, A Robinson… - Journal of Thoracic …, 2017 - jto.org
… treatment with the anti‒PD-1 antibody pembrolizumab … PD-L1 tumor proportion score (TPS)≥
50% and without EGFR mutations or ALK translocations. Results from the primary analysis

… metastatic nonsmall cell lung carcinomas and the correlation between PDL1 expression and treatment effectiveness: an update meta‐analysis of randomized clinical …

Q Zhao, R Xie, S Lin, X You… - BioMed research …, 2018 - Wiley Online Library
… This meta-analysis systematically evaluated the efficacy and safety of anti-PD-1/PD-L1
antibodies for … More importantly, the results of this meta-analysis suggested that anti-PD-1/PD-L1

FP13. 03 IMpower110: updated OS analysis of atezolizumab vs platinum-based chemotherapy as first-line treatment in PD-L1–selected NSCLC

R Herbst, F De Marinis, G Giaccone… - Journal of Thoracic …, 2021 - jto.org
… At the final OS analysis, IMpower110 did not show statistical significance in TC2/3 or IC2/3-WT
patients. Exploratory updated analysis in TC3 or IC3-WT patients showed continued …

[HTML][HTML] Updated overall survival analysis from IMpower110: atezolizumab versus platinum-based chemotherapy in treatment-naive programmed death-ligand 1 …

J Jassem, F de Marinis, G Giaccone… - Journal of Thoracic …, 2021 - Elsevier
analyses in lower PD-L1 expression groups and an updated, … updated analysis of IMpower110
supports using atezolizumab in treatment-naive, metastatic WT NSCLC with high PD-L1