The effect of polymorphism of uric acid transporters on uric acid transport

Z Wang, T Cui, X Ci, F Zhao, Y Sun, Y Li, R Liu… - Journal of …, 2019 - Springer
… Here, we review the effect of the gene polymorphisms on uric acid transporters, which
can provide valuable information for clinical medication and new drug development. …

Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease

K Stark, W Reinhard, M Grassl, J Erdmann… - PloS one, 2009 - journals.plos.org
… loci with association to serum uric acid (UA) levels. … polymorphisms (SNP) markers that
showed association to UA serum levels. In the second study, the same genetic polymorphisms

Tubular urate transporter gene polymorphisms differentiate patients with gout who have normal and decreased urinary uric acid excretion

RJ Torres, E de Miguel, R Bailén, JR Banegas… - The Journal of …, 2014 - jrheum.org
… with gout in patients with normal uric acid excretion. … Gout with uric acid underexcretion is
associated with transporter gene SNP related mainly to tubular reabsorption, whereas uric acid

KLOTHO Gene Polymorphisms G-395A and C1818T Are Associated with Low-Density Lipoprotein Cholesterol and Uric Acid in Japanese Hemodialysis Patients

Y Shimoyama, K Taki, Y Mitsuda, Y Tsuruta… - American journal of …, 2009 - karger.com
… tween KLOTHO gene SNPs … gene SNPs are associated with LDL cholesterol and uric acid.
The mechanism by which KLOTHO gene SNPs are associated with LDL cholesterol and uric

T6092C polymorphism of SLC22A12 gene is associated with serum uric acid concentrations in Korean male subjects

WC Jang, YH Nam, SM Park, YC Ahn, SH Park… - Clinica Chimica …, 2008 - Elsevier
… It has been suggested that the SLC22A12 gene polymorphism may be involved in the …
of the T6092C polymorphism of the SLC22A12 gene on serum uric acid concentrations in …

Serum uric acid levels are associated with polymorphisms in the SLC2A9, SF1, and GCKR genes in a Chinese population

X Sun, F Jiang, R Zhang, S Tang, M Chen… - Acta Pharmacologica …, 2014 - nature.com
genes regulating serum uric acid through genome-wide association studies. The first wave of
discovery of uric acid genes … , ABCG2, and SLC17A3 with uric acid concentrations 15,16,17 …

Uric acid and hypertension: prognostic role and guide for treatment

F Piani, AFG Cicero, C Borghi - Journal of clinical medicine, 2021 - mdpi.com
… Additionally, aldehyde dehydrogenase II (ALDH-2) polymorphisms have been … Other
genetic polymorphisms that regulate SUA levels and associate with hypertension are XOR gene

Serum Uric Acid Levels Are Associated with Polymorphism in the SAA1 Gene in Chinese Subjects

X Xie, YT Ma, YN Yang, XM Li, ZY Fu, YY Zheng… - PLoS …, 2012 - journals.plos.org
… Also, uric acid directly stimulates the … SAA1 genetic polymorphism was associated with
elevated SUA after adjusting for other confounders, indicating that the SAA1 gene polymorphism

Association of Functional Polymorphism rs2231142 (Q141K) in the ABCG2 Gene With Serum Uric Acid and Gout in 4 US Populations: The PAGE Study

L Zhang, KL Spencer, VS Voruganti… - American journal of …, 2013 - academic.oup.com
… common polymorphism rs2231142, which leads to a change from glutamine to lysine in
codon 141 (Q141K) of the ABCG2 gene, is significantly associated with elevated serum uric acid

Uric acid and cardiovascular risk: What genes can say

A Kei, F Koutsouka, A Makri… - International Journal of …, 2018 - Wiley Online Library
… regarding serum uric acid levels and … polymorphisms in the GLUT9 gene have been related
with hyperuricaemia in epidemiologic studies and the T allele of the rs734553 polymorphism