… Oncolytic viruses work by selective replication within tumor cells, causing tumor cell lysis
and release of additional oncolytic virions as well as tumor antigens. One such agent being …

… in urothelial tumor cells only and not in normal urothelial cells. A … cells of both low- and
high-grade papillary urothelial tumors (Fig 6… urothelial cells of both low- and high-grade invasive …

… of circulating tumor cells in the blood and the state of an urothelial cancer after therapies.
Detection of circulating tumor cells might be a valuable serum marker for urothelial cancer …

… of the tumor cell. Ideally the antigen should be expressed at higher levels in tumor tissue …
This preferentially increases the uptake into tumor cells compared with normal cells, and …

… While methods for diagnosis and treatment of typical urothelial cancers (UC) are well-…
The plasmacytoid variant is characterized by tumor cells that resemble plasma cells and/or …

… Of note, luminal cluster-1 UC, which is characterized by lower expression of CD8+ effector
genes and lower PD-L1 expression by tumor-infiltrating immune-cells and by tumor cells, is …

… This score consisted of the percentage of PD-L1–positive tumor cells and infiltrating immune
cells relative to the total number of tumor cells from tumor tissue samples. In the OS analysis …

… for simulation studies of urothelial cancer stem cells and for the … the markers of urothelial
cancer stem cells and possible … expression of CT antigens on tumor cells, and the lack of …

… In this study, PD-L1 positivity was defined as >5 % of tumor-infiltrating immune cells or tumor
cells staining for PD-L1 by IHC. Thirty patients with PD-L1 positivity (IHC 2–3) yielded a 40–…

… That differentiation underlies tumor cell heterogeneity was elegantly demonstrated in … In
contrast, urothelial cancers show a wide degree of heterogeneity within and between tumors and …