Urothelial carcinoma stem cells: current concepts, controversies, and methods

J Hatina, HS Parmar, M Kripnerova, A Hepburn… - Urothelial Carcinoma …, 2018 - Springer
… Several aspects of urothelial cancer stem cell biology could … non-muscle-invasive bladder
cancer patients with a high risk of … expression of the stem cell-specific CK-17 in tumor cells [3]. …

Detection of circulating cancer cells by reverse transcription-polymerase chain reaction for uroplakin II in peripheral blood of patients with urothelial cancer

JJ Lu, Y Kakehi, T Takahashi, XX Wu, T Yuasa… - Clinical cancer …, 2000 - AACR
… Few attempts have been made at the molecular detection of urothelial cancer cells in the …
specific to urothelial cancer or urothelium. In 1990, however, genes that encode urothelium-…

Role of the androgen receptor in urothelial cancer

S Inoue, T Mizushima, H Miyamoto - Molecular and cellular endocrinology, 2018 - Elsevier
… AR signaling in non-neoplastic urothelial cells or urothelial cancer cells. Androgens have
been shown to induce tumorigenesis, tumor progression, and chemoresistance through the AR …

Prognostic significance of PD-L1 expression on tumor cells and tumor-infiltrating mononuclear cells in upper tract urothelial carcinoma

B Zhang, W Yu, X Feng, Z Zhao, Y Fan, Y Meng, S Hu… - Medical Oncology, 2017 - Springer
… -L1) is a cell surface glycoprotein present on tumor cells and immune cells, and its interaction
with … PD-L1 expression on tumor cells or tumor-infiltrating immune cells is closely related to …

VEGF inhibition in urothelial cancer: the past, present and future

S Ghafouri, A Burkenroad, M Pantuck… - World Journal of …, 2021 - Springer
urothelial cancer, bladder adenocarcinoma, germ cell tumors, castrate-resistant prostate
cancer, bladder squamous cell cancer, … of tumor tissue and circulating tumor cells has provided …

[HTML][HTML] Immunotherapy for urothelial cancer: from the diagnostic pathologist's point of view

A Cimadamore, M Scarpelli, F Massari… - Expert Opinion on …, 2020 - Taylor & Francis
… correlated retrospectively The Cancer Genome Atlas (TCGA) urothelial cancer subtype with
… They distinguish tumor cells from normal cells and can stimulate a tumor-specific immune …

[HTML][HTML] Alteration of the LRP1B gene region is associated with high grade of urothelial cancer

S Langbein, O Szakacs, M Wilhelm, F Sukosd… - Laboratory …, 2002 - nature.com
… growth, of a malignant tumor relies on the interaction between tumor cells and their local …
the tumor cells. The grading system reflects the proliferative activity of tumor cells themselves. …

[HTML][HTML] Epithelial plasticity in urothelial carcinoma: Current advancements and future challenges

M Garg - World journal of stem cells, 2016 - ncbi.nlm.nih.gov
urothelial stem cells (UroSCs). Further, recent advancements on the functions of urothelial
cancer stem cells (UroCSCs), a tumor … the regrowth of heterogeneous tumor cells. UroCSCs: …

Cancer stem cells and epithelial–mesenchymal transition in urothelial carcinoma: Possible pathways and potential therapeutic approaches

D Fang, H Kitamura - International Journal of Urology, 2018 - Wiley Online Library
… for simulation studies of urothelial cancer stem cells and for the … the markers of urothelial
cancer stem cells and possible … expression of CT antigens on tumor cells, and the lack of …

Vaccine approaches to treat urothelial cancer

GC Giudice, GP Sonpavde - Human Vaccines & …, 2024 - Taylor & Francis
… Different types of whole cells or fragments have been tested, such as tumor cells and
modified autologous cancer or immune cells. Tumor cell vaccines are killed tumor cells injected …