Anti-inflammatory effects of ursodeoxycholic acid by lipopolysaccharide-stimulated inflammatory responses in RAW 264.7 macrophages
… Inflammatory response is a physiological process against … a critical role in inflammatory
responses through the production … releasing various pro-inflammatory cytokines including tumor …
responses through the production … releasing various pro-inflammatory cytokines including tumor …
Ursodeoxycholic acid (UDCA) mitigates the host inflammatory response during Clostridioides difficile infection by altering gut bile acids
JA Winston, AJ Rivera, J Cai, R Thanissery… - Infection and …, 2020 - Am Soc Microbiol
… of ursodiol pretreatment on the host inflammatory response during CDI. We interrogated …
inflammatory response at day 2 postchallenge using a mouse-specific panel of inflammatory …
inflammatory response at day 2 postchallenge using a mouse-specific panel of inflammatory …
Ursodeoxycholic acid and lithocholic acid exert anti-inflammatory actions in the colon
JBJ Ward, NK Lajczak, OB Kelly… - American Journal …, 2017 - journals.physiology.org
… secondary bile acid, ursodeoxycholic acid (UDCA), has well-established anti-inflammatory
and … We aimed to investigate regulation of colonic inflammatory responses by UDCA and to …
and … We aimed to investigate regulation of colonic inflammatory responses by UDCA and to …
Immunomodulatory effects of ursodeoxycholic acid on immune responses
M Yoshikawa, T Tsujii, K Matsumura, J Yamao… - Hepatology, 1992 - journals.lww.com
… the usefulness of ursodeoxycholic acid as a potentially bene… direct effects of ursodeoxycholic
acid on immunoglobulin and … It was demonstrated that ursodeoxycholic acid suppressed …
acid on immunoglobulin and … It was demonstrated that ursodeoxycholic acid suppressed …
Ursodeoxycholic acid inhibits inflammatory responses and promotes functional recovery after spinal cord injury in rats
… The aim of this study was to investigate the anti-inflammatory effects by ursodeoxycholic
acid (UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …
acid (UDCA) in rats with a spinal cord injury (SCI). A moderate mechanical compression injury …
[HTML][HTML] 24-nor-ursodeoxycholic acid ameliorates inflammatory response and liver fibrosis in a murine model of hepatic schistosomiasis
M Sombetzki, CD Fuchs, P Fickert, CH Österreicher… - Journal of …, 2015 - Elsevier
… UDCA as well as norUDCA attenuated the inflammatory response in livers of S. mansoni
infected mice, but exclusively norUDCA changed cellular composition and reduced size of …
infected mice, but exclusively norUDCA changed cellular composition and reduced size of …
Ursodeoxycholic acid: a promising therapeutic target for inflammatory bowel diseases?
SJ Keely, CJ Steer… - American Journal of …, 2019 - journals.physiology.org
… of ursodeoxycholic acid (UDCA) in inflammatory bowel … , thereby perpetuating the
inflammatory response. Preclinical … UDCA can dampen mucosal inflammatory responses, prevent …
inflammatory response. Preclinical … UDCA can dampen mucosal inflammatory responses, prevent …
Ursodeoxycholic acid inhibits TNFα-induced IL-8 release from monocytes
AM O'Dwyer, NK Lajczak, JA Keyes… - American Journal …, 2016 - journals.physiology.org
… Monocytes are critical to the pathogenesis of inflammatory bowel disease (IBD) as they …
inflammatory response. Ursodeoxycholic acid (UDCA), a naturally occurring bile acid with anti-…
inflammatory response. Ursodeoxycholic acid (UDCA), a naturally occurring bile acid with anti-…
The secondary bile acids, ursodeoxycholic acid and lithocholic acid, protect against intestinal inflammation by inhibition of epithelial apoptosis
NK Lajczak‐McGinley, E Porru, CM Fallon… - Physiological …, 2020 - Wiley Online Library
… the inflammatory response. Given the importance of increased apoptosis and dysregulated
epithelial barrier function in the pathogenesis of IBD, there is a great deal of interest in its …
epithelial barrier function in the pathogenesis of IBD, there is a great deal of interest in its …
Ursodeoxycholic acid and bile-acid mimetics as therapeutic agents for cholestatic liver diseases: an overview of their mechanisms of action
R Poupon - Clinics and research in hepatology and …, 2012 - Elsevier
… Indeed, activation of the glucocorticoid receptor represses a large set of functionally related
inflammatory response genes by disrupting the p65/IFN regulatory factor complexes required …
inflammatory response genes by disrupting the p65/IFN regulatory factor complexes required …
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