Erlotinib: a new therapeutic approach for non-small cell lung cancer
P Bonomi - Expert opinion on investigational drugs, 2003 - Taylor & Francis
… majority of lung cancer cases are classified as non-small cell … IV non-small cell lung cancer
(NSCLC) [5], and the use of … to 16% of patients with stage III lung cancer [6]. Despite modest …
(NSCLC) [5], and the use of … to 16% of patients with stage III lung cancer [6]. Despite modest …
Erlotinib in lung cancer—molecular and clinical predictors of outcome
… response to erlotinib; however, those who had never smoked had a significant survival benefit
from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer, we …
from erlotinib. To clarify the role of EGFR in the outcome of non–small-cell lung cancer, we …
Erlotinib in previously treated non–small-cell lung cancer
FA Shepherd, J Rodrigues Pereira… - New England journal …, 2005 - Mass Medical Soc
… to determine whether the epidermal growth factor receptor inhibitor erlotinib prolongs
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …
survival in non–small-cell lung cancer after the failure of first-line or second-line chemotherapy. …
Determinants of tumor response and survival with erlotinib in patients with non—small-cell lung cancer
R Pérez-Soler, A Chachoua, LA Hammond… - Journal of clinical …, 2004 - ascopubs.org
… This phase II study of erlotinib in patients with HER1/EGFR-expressing non–small-cell lung
cancer previously treated with platinum-based chemotherapy evaluated tumor response, …
cancer previously treated with platinum-based chemotherapy evaluated tumor response, …
Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
F Cappuzzo, T Ciuleanu, L Stelmakh, S Cicenas… - The lancet …, 2010 - thelancet.com
… advanced non-small-cell lung cancer (NSCLC) is … erlotinib has proven efficacy and tolerability
in second-line NSCLC. We designed the phase 3, placebo-controlled Sequential Tarceva …
in second-line NSCLC. We designed the phase 3, placebo-controlled Sequential Tarceva …
Erlotinib in the treatment of advanced non-small cell lung cancer: an update for clinicians
Y Wang, G Schmid-Bindert… - Therapeutic advances in …, 2012 - journals.sagepub.com
… treatment of advanced non-small cell lung cancer (NSCLC). Erlotinib and gefitinib, two small
… these tyrosine kinase inhibitors, with a focus on erlotinib, as first-line treatment towards a …
… these tyrosine kinase inhibitors, with a focus on erlotinib, as first-line treatment towards a …
Erlotinib for frontline treatment of advanced non–small cell lung cancer: a phase II study
G Giaccone, M Gallegos Ruiz, T Le Chevalier… - Clinical Cancer …, 2006 - AACR
… Purpose: Erlotinib has proven activity in pretreated patients with advanced non–small cell
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
lung cancer (NSCLC). We evaluated erlotinib in the frontline treatment of advanced NSCLC …
The role of erlotinib (Tarceva, OSI 774) in the treatment of non-small cell lung cancer
R Perez-Soler - Clinical cancer research, 2004 - AACR
… Erlotinib (Tarceva) is a reversible and highly specific inhibitor of epidermal growth factor …
with EGFR-positive non-small cell lung cancer after failure of platinum-containing chemotherapy …
with EGFR-positive non-small cell lung cancer after failure of platinum-containing chemotherapy …
[HTML][HTML] Adherence, exposure and patients' experiences with the use of erlotinib in non-small cell lung cancer
L Timmers, CCLM Boons, J Moes-Ten Hove… - Journal of cancer …, 2015 - Springer
… Erlotinib is an orally administered tyrosine kinase inhibitor used for treatment of non-small
cell lung cancer. Understanding actual use of medication is essential for optimizing treatment …
cell lung cancer. Understanding actual use of medication is essential for optimizing treatment …
Clinical pharmacokinetics of erlotinib in patients with solid tumors and exposure‐safety relationship in patients with non–small cell lung cancer
JF Lu, SM Eppler, J Wolf, M Hamilton… - Clinical …, 2006 - Wiley Online Library
… By use of a 1-compartment model with first-order absorption, the influence of demographic
… erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …
… erlotinib exposure in non-small cell lung cancer patients treated with single-agent erlotinib. …
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