Use of fluorescence to guide resection or biopsy of primary brain tumors and brain metastases

S Marbacher, E Klinger, L Schwyzer, I Fischer… - Neurosurgical …, 2014 - thejns.org
… -ALA)–induced intraoperative fluorescence has proven to be a … The clinical utility of 5-ALA
in resection of brain tumors other … fluorescence in a cohort of patients with primary brain tumors

Fluorescence-guided surgery: a review on timing and use in brain tumor surgery

AJ Schupper, M Rao, N Mohammadi, R Baron… - Frontiers in …, 2021 - frontiersin.org
… ICG was injected intravenously into tumor-bearing rats, the tumor fluoresced intensely at
60–… rat brain tumor from normal parenchyma with adequate tumor to normal brain background …

The clinical use of fluorescein in neurosurgery: the localization of brain tumors

GE Moore, WT Peyton, LA French, WW Walker - Journal of neurosurgery, 1948 - thejns.org
… This report concerns the clinical use of fluorescein as an aid in the … Although brain tumors
can usually be localized by … a more rapid quenching of fluorescence by the tumor extract. …

Fluorescence lifetime spectroscopy for guided therapy of brain tumors

PV Butte, AN Mamelak, M Nuno, SI Bannykh, KL Black… - Neuroimage, 2011 - Elsevier
… We noticed that the use of a spacer between the optical probe and tissue and presence of
a slit in the spacer which enabled suction to remove the blood in the optical path during the …

Intraoperative fluorescence imaging for personalized brain tumor resection: current state and future directions

E Belykh, NL Martirosyan, K Yagmurlu, EJ Miller… - Frontiers in …, 2016 - frontiersin.org
… current fluorescence techniques used in neurosurgical practice for brain tumor patients as
… of fluorescein for glioma surgery was in 1948 (20), fluorescein use in brain tumor surgery is …

[PDF][PDF] Clinical Guidelines for Application of Intraoperative Fluorescence Diagnosis in Brain Tumor Surgery

A Potapov, S Goryaynov, V Okhlopkov… - Voprosy …, 2015 - researchgate.net
… of intraoperative fluorescence diagnosis and fluorescence … techniques, in surgery of various
brain tumors. On the basis of … the use of fluorescence diagnosis in surgery of brain tumors. …

Intraoperative fluorescence staining of malignant brain tumors using 5-aminofluorescein-labeled albumin

P Kremer, M Fardanesh, R Ding, M Pritsch… - Operative …, 2009 - journals.lww.com
… , so that the fluorescence of the brain tumor was blotted out and the tumor borders blurred
… , because it is inexpensive, easy to use, not toxic, and accounts for brain shift. In addition, …

Fluorescence-guided surgery of metastatic brain tumors using fluorescein sodium

T Okuda, K Kataoka, T Yabuuchi, H Yugami… - Journal of clinical …, 2010 - Elsevier
… control, we have assessed the use of fluorescence-guided surgery of metastatic brain
fluorescence-guided surgery with GTR achieved successful local control of metastatic brain tumors

Intraoperative delineation of primary brain tumors using time-resolved fluorescence spectroscopy

PV Butte, Q Fang, JA Jo, WH Yong… - … of biomedical optics, 2010 - spiedigitallibrary.org
… The overall objective of this study is to investigate the use of TR-… brain tumor (glioma)
were included in this study. The patients were scheduled for surgical removal of the brain tumor

Predicting the “usefulness” of 5-ALA-derived tumor fluorescence for fluorescence-guided resections in pediatric brain tumors: a European survey

…, European ALA Pediatric Brain Tumor Study Group - Acta …, 2014 - Springer
… on with Gliolan in a compassionate-use setting compiled from three neurosurgical … brain
tumor pathologies. Results were equivocal as only eight of 14 tumors displayed fluorescence, …