… This review focuses on the role of aromatase, ovarian steroids and stem-progenitor cells
in the pathogenesis of uterine leiomyoma, and discusses the therapeutic implications of the …

… leiomyoma management. In the present review, we aimed to give an overview of pathogenetic
concepts of uterine leiomyoma … the medical treatments for uterine leiomyoma that are FDA-…

… and remodeling is critical for developing new therapeutics for uterine leiomyoma. … in
leiomyoma, we propose that ECM should be considered as a crucial target for future therapeutics. …

… therapeutic effect on uterine leiomyomas. Raloxifene has been showed to enhance the
shrinkage of uterine leiomyomas … the effect of raloxifene on uterine leiomyomas showed that the …

… Although uterine fibroids are known to be benign tumors with reduced vascularization, …
linked to leiomyoma growth and vascularization, we discuss possible therapeutic implications in …

… of uterine leiomyomas, their impact on ART and pregnancy and leiomyoma therapeutics
was … The literature regarding uterine leiomyomas and their impact on Assisted Reproductive …

… identified SERMs as a potential therapeutic strategy for the treatment of uterine leiomyoma.
… Efficacy and safety considerations in women with uterine leiomyomas treated with …

… Uterine leiomyomas are extremely common neoplasms that by the age of 50 are found in
the uterus of almost 70% of white women and more than 80% of women of African ancestry. …

… The underlying processes driving the transformation of a myocyte into a uterine fibroid are
not completely understood. However, several genetic, hormonal, and biologic factors have …

… Uterine leiomyomas or, as frequently called, fibroids or myomas, are the most common
solid pelvic tumors of the genital tract in women. Because of their frequency and bothersome …