Chronic helminth infections impair pneumococcal vaccine responses
N Apiwattanakul, PG Thomas, AR Iverson… - Vaccine, 2014 - Elsevier
… of helminth infections in the countries targeted for vaccine might have on vaccine effectiveness…
might interfere with immunity to and efficacy of pneumococcal vaccines. We elected to test …
might interfere with immunity to and efficacy of pneumococcal vaccines. We elected to test …
The yin and yang of human soil-transmitted helminth infections
… Despite high efficacy, animals showed residual levels of infection that dented confidence
in … The absence of vaccines for any human helminth infection can be attributed to a lack of …
in … The absence of vaccines for any human helminth infection can be attributed to a lack of …
Pre-existing helminth infection impairs the efficacy of adjuvanted influenza vaccination in mice
W Hartmann, ML Brunn, N Stetter, G Gabriel, M Breloer - Plos one, 2022 - journals.plos.org
… infection of vaccination efficacy should be addressed [13, 14]… with vaccination efficacy by
underlying helminth infections in … -infected mice as a model for chronic human filarial infections […
underlying helminth infections in … -infected mice as a model for chronic human filarial infections […
Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance
D Elias, S Britton, A Kassu, H Akuffo - Expert review of anti-infective …, 2007 - Taylor & Francis
… Most areas of high TB incidence and poor TB vaccine efficacy have a high prevalence of
intestinal helminth infections. Such infections have been shown to cause a range of …
intestinal helminth infections. Such infections have been shown to cause a range of …
Promising technologies in the field of helminth vaccines
… will summarize various helminth vaccination techniques and compare their efficacy for …
no RNA vaccines developed against helminthic infections, however DNA vaccines have been …
no RNA vaccines developed against helminthic infections, however DNA vaccines have been …
Immunology of parasitic helminth infections
AS MacDonald, MI Araujo, EJ Pearce - Infection and immunity, 2002 - Am Soc Microbiol
… and allow the rational development of more efficacious vaccines. Basic research on model
… The absence of vaccines, the amenability of several mouse models of helminth infection to …
… The absence of vaccines, the amenability of several mouse models of helminth infection to …
A combination of deworming and prime-boost vaccination regimen restores efficacy of vaccination against influenza in helminth-infected mice
N Stetter, W Hartmann, ML Brunn… - Frontiers in …, 2021 - frontiersin.org
… of helminth-infected individuals to vaccinations may be impaired as well. Here we study the
impact of helminth-induced immunomodulation on vaccination efficacy … sigmodontis infection …
impact of helminth-induced immunomodulation on vaccination efficacy … sigmodontis infection …
Impact of helminth infections during pregnancy on vaccine immunogenicity in Gabonese infants
J Flügge, AA Adegnika, YJ Honkpehedji, TL Sandri… - Vaccines, 2020 - mdpi.com
… The vaccination may not have been efficacious, but in our assay the level of protection
against tetanus is indicated at 0.01 IU/mL [56], so the children’s levels are above the cut-off for …
against tetanus is indicated at 0.01 IU/mL [56], so the children’s levels are above the cut-off for …
Malaria vaccine efficacy: overcoming the helminth hurdle
JV Cruz-Chan, M Rosado-Vallado… - … Review of Vaccines, 2010 - Taylor & Francis
… Interestingly, the authors found that helminth infection dramatically reduced DNA vaccine
immunogenicity, while immunization with irradiated sporozoites was able to induce a high level …
immunogenicity, while immunization with irradiated sporozoites was able to induce a high level …
Control of Important Helminthic Infections: VaccineDevelopment as Part of the Solution
R Bergquist, S Lustigman - Advances in parasitology, 2010 - Elsevier
… is no vaccine commercially available for any human parasitic infection yet, recent progress
in vaccine … In spite of the high efficacy of this vaccine, which has the capability to wipe out …
in vaccine … In spite of the high efficacy of this vaccine, which has the capability to wipe out …