Role of the vagus nerve in the development and treatment of diet‐induced obesity

G De Lartigue - The Journal of physiology, 2016 - Wiley Online Library
… to the vagus nerve for the treatment of obesity are proposed. In … vagus nerve is involved in
the development of obesity and it is proving to be an attractive target for the treatment of obesity

The use of electrical stimulation of the vagus nerve to treat morbid obesity

M Roslin, M Kurian - Epilepsy & Behavior, 2001 - Elsevier
… would need to target the central nervous system, and the gut–… vagus nerve may provide
an accessible input to the central nervous system and a potential treatment strategy for morbid

The evolving obesity challenge: targeting the vagus nerve and the inflammatory reflex in the response

VA Pavlov - Pharmacology & therapeutics, 2021 - Elsevier
… These findings considerably change the view of obesity as a … driver of metabolic derangements
in obesity and MetS, and a … the role of the nervous system and the vagus nerve-based …

Effect of vagal nerve blockade on moderate obesity with an obesity-related comorbid condition: the ReCharge study

JM Morton, SN Shah, BM Wolfe, CM Apovian, CJ Miller… - Obesity surgery, 2016 - Springer
Vagal nerve blockade (vBloc) therapy was shown to be a safe and effective treatment for
moderate to severe obesity. … in the prespecified subgroup of patients with moderate obesity. …

The vagus nerve, food intake and obesity

HR Berthoud - Regulatory peptides, 2008 - Elsevier
… and prevention of obesity [3]. The vagus nerve is arguably the most important link between
the gut and the brain, and the present review attempts to clarify the role of this nerve in the …

Vagal nerve function in obesity: therapeutic implications

JG Kral, W Paez, BM Wolfe - World journal of surgery, 2009 - Springer
Obesity surgery circumvents powerful redundant mechanisms … nervous system function
and the brain–gut axis. We review the functional anatomy and the importance of the vagus nerve

Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity: the ReCharge randomized clinical trial

S Ikramuddin, RP Blackstone, A Brancatisano, J Toouli… - Jama, 2014 - jamanetwork.com
… In this study of patients with morbid obesity, the percentage of excess weight loss among
participants treated with vagal block did not meet either of the coprimary efficacy objectives, …

Gut-brain communication and obesity: understanding functions of the vagus nerve

HR Berthoud, VL Albaugh… - The Journal of clinical …, 2021 - Am Soc Clin Investig
… Clearly, many scientists were attracted to the subdiaphragmatic vagus nerves and branches
… branch of the vagus nerve as a tool to study the role of the vagus nerve in liver function (for …

A review of vagus nerve stimulation as a therapeutic intervention

RL Johnson, CG Wilson - Journal of inflammation research, 2018 - Taylor & Francis
… of the vagus nerve and its projections has been discovered through tract tracing of the rat
vagus and is … A broader concern is the role vagal tone plays in metabolic disease and obesity. …

Vagus nerve stimulation in the treatment of morbid obesity

M Roslin, M Kurian - Vagus nerve stimulation, 2002 - api.taylorfrancis.com
… ) vagus nerve provides the bulk of innervation to the proximal stomach. In contrast, the posterior
trunk (right vagus nerve) … Figure 6.2 Vagus nerve stimulation for the treatment of obesity. …