Structure, expression and divergence of T-cell receptor β-chain variable regions

P Patten, T Yokota, J Rothbard, Y Chien, K Arai… - Nature, 1984 - nature.com
… hypervariable (nonconserved) regions, according to the precedent … -chain variable regions
appear to diverge between species much more rapidly than immunoglobulin variable regions, …

Sequences and diversity of human T cell receptor beta chain variable region genes.

N Kimura, B Toyonaga, Y Yoshikai, F Triebel… - The Journal of …, 1986 - rupress.org
… 22 human nucleotide sequences encoding the variable region of the TcR '6 chain have
been analyzed in this study (Figs. 1 and 2). Three appear to be the result of incomplete …

Complexity of human T-cell antigen receptor β-chain constant- and variable-region genes

JE Sims, A Tunnacliffe, WJ Smith, TH Rabbitts - Nature, 1984 - nature.com
… light chains. The similarity of the T-cell β-chain gene system to the immunoglobulin
genes has been further demonstrated by the recent observation of variable- and constant-region

Diversity and structure of human T-cell receptor beta-chain variable region genes.

P Concannon, LA Pickering… - Proceedings of the …, 1986 - National Acad Sciences
… T-cell receptor E-chain variable region (Vp) gene segment sequences… chain and light chain
variable region (VH and VL) repertoires. Variability plots comparing these human Vp regions

Sequences and repertoire of the human T cell receptor α and β chain variable region genes in thymocytes

N Kimura, B Toyonaga, Y Yoshikai… - European journal of …, 1987 - Wiley Online Library
… of the human T cell receptor α and β chain variable region genes in thymocytes … p chain
cDNA provided primary structural evidence for the existence of variable and constant regions

T-cell receptor β-chain expression: dependence on relatively few variable region genes

MA Behlke, DG Spinella, HS Chou, W Sha, DL Hartl… - Science, 1985 - science.org
… of the number of expressed germline V β genes to be 18 with an … β-chain diversity appears
to be generated from a limited V β gene pool primarily by extensive variability at the variable

Rearrangement of two distinct T-cell γ-chain variable-region genes in human DNA

MP Lefranc, A Forster, TH Rabbitts - Nature, 1986 - nature.com
… a y-chain gene probe" and a set of three y-chain variable (V) … to be confined to VJ (joining)
regions". In contrast, human T-… to the two y-chain constant (C) region genes". Here we report …

Subgroups of variable region genes of beta chains of T-cell receptors for antigen.

M Schiffer, TT Wu, EA Kabat - Proceedings of the National …, 1986 - National Acad Sciences
… The use of variability plots on the assumption that the1 chains are a single population … the
variable region. Most of the variability in the expressed 13 chains would be created by variable-…

Residues of the variable region of the T-cell-receptor β-chain that interact with S. aureus toxin superantigens

Y Choi, A Herman, D DiGiusto, T Wade, P Marrack… - Nature, 1990 - nature.com
… determined by a combination of the variable elements of o- and ß-chains of the TCR"". …
bearing particular variable-region ß-chain (VB) elements irrespective of the other variable com…

Structure and diversity of the human T-cell receptor β-chain variable region genes

JP Tillinghast, MA Behlke, DY Loh - Science, 1986 - science.org
… n-chain repertoire and contrast this variability to the known murine ,B-chain repertoire, 15
independent complementary DNA (cDNA) clones containing TCR ,B-chain variable region (Vp…