Variation in treatment of neonatal abstinence syndrome in US children's hospitals, 2004–2011

SW Patrick, HC Kaplan, M Passarella, MM Davis… - Journal of …, 2014 - nature.com
… We found variation in hospital in treatment for NAS among … Our study aimed to evaluate
treatment variation among … complex newborns and newborns treated for withdrawal after 7 days …

Hospital variation in neonatal abstinence syndrome incidence, treatment modalities, resource use, and costs across pediatric hospitals in the United States, 2013 to …

CE Milliren, M Gupta, DA Graham, P Melvin… - Hospital …, 2018 - publications.aap.org
treated pharmacologically with wide variation in hospital rates of pharmacotherapy (range:
13%–90%). Pharmacologically-treated … Total costs for pharmacologically-treated neonates …

Neonatal abstinence syndrome: presentation and treatment considerations

K Kaltenbach, HE Jones - Journal of addiction medicine, 2016 - journals.lww.com
… exposure at delivery, NAS treatment protocols, the need … treatment, and the occurrence
and treatment of NAS. This study provides an in-depth examination of NAS, including variations

A multicenter cohort study of treatments and hospital outcomes in neonatal abstinence syndrome

ES Hall, SL Wexelblatt, M Crowley, JL Grow… - …, 2014 - publications.aap.org
variation, infants receiving protocol-based weans experienced a significantly shorter duration
of opioid treatment … opioid treatment or length of stay when we compared those treated with …

Increasing incidence and geographic distribution of neonatal abstinence syndrome: United States 2009 to 2012

SW Patrick, MM Davis, CU Lehmann… - Journal of …, 2015 - nature.com
… We found significant geographic variation in NAS that parallels variations in OPR prescription…
of stay and treatment of neonatal abstinence syndrome. JAMA 2013; 309 (17): 1821–1827. …

Variations in opioid receptor genes in neonatal abstinence syndrome

EM Wachman, MJ Hayes, R Sherva, MS Brown… - Drug and alcohol …, 2015 - Elsevier
Background There is significant variability in the severity of neonatal abstinence syndrome (NAS)
due to in-utero opioid exposure. We wanted to determine if single nucleotide …

Variations and similarities in clinical management of neonatal abstinence syndrome: findings of a Canadian survey

K Murphy, H Coo, R Warre, V Shah… - Paediatrics & Child …, 2017 - academic.oup.com
… monitoring and treatment of NAS (although the Ontario Provincial Council for Maternal and
Child Health has published guidelines for that province (6)). If such practice variations were …

Variations in infant CYP2B6 genotype associated with the need for pharmacological treatment for neonatal abstinence syndrome in infants of methadone-maintained …

H Mactier, P McLaughlin, C Gillis… - American journal of …, 2017 - thieme-connect.com
… Background Neonatal abstinence syndrome (NAS) in infants of … We investigated whether
variation in infant genotype is … according to treatment of neonatal abstinence syndrome (NAS) …

A state-level study of opioid use disorder treatment access and neonatal abstinence syndrome

ER Wolf, ST Tong, RT Sabo, SH Woolf, K Abbinanti… - BMC pediatrics, 2019 - Springer
… Between states, there was wide variation in access to opioid use disorder treatment. The
states with the highest levels of access tended to be in the Northeast and the Pacific Northwest. …

Epigenetic variation in the mu-opioid receptor gene in infants with neonatal abstinence syndrome

EM Wachman, MJ Hayes, BM Lester, N Terrin… - The Journal of …, 2014 - Elsevier
… DNA samples from cord blood or saliva were analyzed for 86 infants who were being treated
… NAS outcome measures, including need for treatment, treatment with ≥2 medications, and …