Amiodarone and Dronedarone Causes Liver Injury with Distinctly Different Clinical Presentations

A Pop, D Halegoua-DeMarzio, H Barnhart… - Digestive Diseases and …, 2024 - Springer
Amiodarone hepatotoxicity resembles that seen in alcohol … two drugs leading to different
mechanisms of hepatotoxicity. … bound, accumulating in many organs leading to its prolonged half…

Hyperacute drug-induced hepatitis with intravenous amiodarone: case report and review of the literature

M Nasser, TR Larsen, B Waanbah, I Sidiqi… - Drug, healthcare and …, 2013 - Taylor & Francis
amiodarone hepatotoxicity versus other proposed or even unknown mechanisms ( Figure
2 ). Six fatal cases of IV amiodarone hepatitis … in part by the acute organ failure of the liver ( …

The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells

A Zahno, K Brecht, R Morand, S Maseneni… - Biochemical …, 2011 - Elsevier
amiodarone's hepatotoxicity. Since CYP3A4 inducers are used frequently and
amiodarone-associated hepatotoxicity … and organ toxicity due to impaired mitochondrial function …

Amiodarone concentrations in plasma and fat tissue during chronic treatment and related toxicity

C Lafuente‐Lafuente, JC Alvarez… - British journal of …, 2009 - Wiley Online Library
Amiodarone side-effects may affect numerous organs: most frequently thyroid, skin and
eyes, but also lung, liver, heart, and peripheral … -related severe subacute hepatitis (Table S1). …

Low-dose amiodarone-induced fatal liver failure

E Akbal, H Batgi, E Koçak, T Canatan… - Drug and Chemical …, 2013 - Taylor & Francis
Amiodarone is associated with many adverse effects that involve different organs. The most
Amiodarone was discontinued after admission, and hepatitis and renal failure were treated …

[HTML][HTML] Acute fulminant hepatic failure and renal failure induced by oral amiodarone: A case report and literature review

N Campbell, K Agarwal, M Alidoost, JA Miskoff… - Cureus, 2020 - ncbi.nlm.nih.gov
… of amiodarone associated with hepatotoxicity has not been elucidated, severe cases of
amiodarone hepatotoxicity … the first doses of amiodarone to prevent irreversible organ damage. …

[PDF][PDF] Amiodarone‐induced hepatic phospholipidosis: a morphological alteration independent of pseudoalcoholic liver disease

B Guigui, S Perrot, JP Berry, J Fleury‐Feith… - …, 1988 - Wiley Online Library
Amiodarone-induced hepatotoxicity has also been recognized (4) and consists of mild liver
… in numerous organs in man or in laboratory animals after administration of amiodarone and …

[引用][C] Fatal Acute-on-Chronic Liver Failure from Amiodarone Toxicity

S Treeprasertsuk, P Komolmit - Thai J Gastroenterol, 2014

[HTML][HTML] Acute hepatitis after amiodarone infusion

P Fonseca, A Dias, H Gonçalves… - World Journal of …, 2015 - ncbi.nlm.nih.gov
hepatitis induced by intravenous amiodarone. Among the few cases reported in literature of
idiosyncratic reactions to intravenous amiodaroneamiodarone exposure and acute hepatitis

Role of oxidative stress in amiodarone-induced toxicity

JSM Sarma, H Pei… - Journal of Cardiovascular …, 1997 - journals.sagepub.com
… significantly different except in the spleen where they increased after amiodarone treatment
(… Conclusions: The results show that amiodarone-induced pulmonary and hepatic toxicity is …