… related to the influence of an allyl substituent at C-4, an OH … These studies showed that the
antifungal activity of 2 was not … revealed that the antifungal activity of the eugenol analogues …

… , and their antifungal activity evaluated. The key … antifungal activity, especially against
filamentous fungi. Expressed as the minimum inhibition concentration (MIC) in μmol/L, the activity …

… the antifungal activity of the test compounds and the physicochemical parameters of the varied
substituents … and the incorporation of substituents with optimal physicochemical properties …

… is not essential for the activity but it is beneficial. In general, the order of the effect of substituents
at C4 of the phenyl ring on the antifungal activity was NO2 > heterocyclic rings > Cl > H. …

… The incidence of candidemia in the US and Europe varies between 1.9 and … antifungal
activity could not be explained reasonably in the light of theories of the influence of substituents …

… , 40−43, 45−47, and 49 showed varying degrees of antifungal activity (Table 1) while other …
that have aromatic chloro and methoxy substituents show a slightly weaker activity than 1. It is …

… 10) showed in vitro antifungal activity comparable to or higher … under isocratic conditions with
varying amounts of an organic … the substituent variability influence on the biological activity. …

… substituent and compound 26 having a para-phenyl groups as R1 showed lesser activities,
… glabrata according to the literature protocol [17] and found that compounds showed varying …

… in water and their antifungal activity against B. cinerea. As shown in Table 4 the antifungal
activity of … The Vw term indicates that the smaller substituent Y in size, the higher the activity. …

… antifungal activity also have an alkyl substituent at this position. Clomiphene (Fig 4, molecule
20), a commercially available SERM that has a chloride instead of an alkyl substituent … vary …