Cellular mechanism of action by a novel vasoconstrictor endothelin in cultured rat vascular smooth muscle cells

Y Hirata, H Yoshimi, S Takata, TX Watanabe… - Biochemical and …, 1988 - Elsevier
… of cultured porcine endothelial cells, and its effects … vascular smooth muscle cells (VSMC).
Binding of 125 I-labeled-pET to rat VSMC was time- and temperature-dependent and the cell-…

Mechanisms of action of estrogen receptors in vascular cells: relevance for menopause and aging

T Simoncini - Climacteric, 2009 - Taylor & Francis
mechanism of action of ERs. In fact, estrogen triggers a number of rapid actions in vascular
cells, inducing vasodilatation, exerting anti-inflammatory activity, regulating vascular cell

Caffeine′ s Vascular Mechanisms of Action

D Echeverri, FR Montes, M Cabrera… - … journal of vascular …, 2010 - Wiley Online Library
… In vascular smooth muscle cells its effect is predominantly a … in the vascular tissue to
produce vasoconstriction. In this paper the main mechanisms of action of caffeine on the vascular

Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action

L Hénaut, C Boudot, ZA Massy… - Cardiovascular …, 2014 - academic.oup.com
Vascular calcification (VC) contributes to morbidity and mortality in patients with chronic …
cell phenotype, and mineral deposition in human vascular smooth muscle cells (h-VSMCs). …

Reactive oxygen species: physiological roles in the regulation of vascular cells

D Vara, G Pula - Current molecular medicine, 2014 - ingentaconnect.com
… endothelial cell proliferation and migration, mediate platelet … Our understanding of ROS
chemistry and cell biology has … , functions and molecular mechanisms of action of different ROS …

Modulation of endothelial cell function by normal polyspecific human intravenous immunoglobulins: a possible mechanism of action in vascular diseases

C Xu, B Poirier, JPD Van Huyen, N Lucchiari… - The American journal of …, 1998 - Elsevier
cells of the vascular bed is not clear as yet. We have investigated the effect of IVIg on thein
vitro activation of human endothelial cells, as assessed by cell … and vascular cellular adhesion …

Vasodilator effect and mechanism of action of vascular endothelial growth factor in skin vasculature

H Ashrafpour, N Huang, PC Neligan… - American Journal …, 2004 - journals.physiology.org
vascular effects and mechanism of action of acute VEGF 165 treatment in the skin vasculature.
… in the skin vasculature, and the postreceptor mechanism involves activation of PLC and …

Discovery and mechanism of action of a novel series of apoptosis inducers with potential vascular targeting activity

S Kasibhatla, H Gourdeau, K Meerovitch, J Drewe… - Molecular cancer …, 2004 - AACR
… versus resting cells. Interestingly, these … cell capillary tubules in vitro and affect functional
vasculature to induce tumor necrosis in vivo and are thus likely to work as tumor vasculature

The mechanisms of action of PPARs

J Berger, DE Moller - Annual review of medicine, 2002 - annualreviews.org
… -induced vascular cell adhesion and to suppress monocyte-macrophagemigration has
also been recently reported as a possible mechanism ofantiatherosclerosis efficacy. …

Vascular endothelial growth factor and the eye: biochemical mechanisms of action and implications for novel therapies

LP Aiello - Ophthalmic research, 1997 - karger.com
… However, the exact molecules involved and their mechanisms of action have remained …
Vascular endothelial growth factor has been implicated as a major mediator of intraocular …