Vascular mimicry: changing the therapeutic paradigms in cancer

N Fathi Maroufi, S Taefehshokr, MR Rashidi… - Molecular biology …, 2020 - Springer
… drugs in a new process called vascular mimicry (VM). The studies have revealed that cells
resistant to anti-angiogenesis cancer therapies are more capable of forming VMs in the in vivo …

[HTML][HTML] Tumor cell vasculogenic mimicry: from controversy to therapeutic promise

REB Seftor, AR Hess, EA Seftor, DA Kirschmann… - The American journal of …, 2012 - Elsevier
… Since VM was introduced as a novel paradigm for melanoma … vascular, stem cell, and
hypoxia-related signaling pathways, each deserving serious consideration as potential therapeutic

Tumor cell vascular mimicry: Novel targeting opportunity in melanoma

MJC Hendrix, EA Seftor, REB Seftor, JT Chao… - … & therapeutics, 2016 - Elsevier
… One of the new paradigms that has … “vasculogenic mimicry”, also referred to as “vascular
mimicry” (VM), and describes the de novo formation of perfusable, matrix-rich, vasculogenic-like …

Molecular pathways: vasculogenic mimicry in tumor cells: diagnostic and therapeutic implications

DA Kirschmann, EA Seftor, KM Hardy, REB Seftor… - Clinical cancer …, 2012 - AACR
vasculogenic mimicry (VM) describes the functional plasticity of aggressive cancer cells
forming de novo vascular … the new paradigms that has emerged, called “vasculogenic mimicry,” …

Vascular mimicry: concepts and implications for anti-angiogenic therapy

JM Dunleavey, AC Dudley - Current angiogenesis, 2012 - ingentaconnect.com
As in normal tissues, solid tumors depend on vascular networks to supply blood, oxygen, and
nutrients. Tumor blood vessels are formed by common processes of neovascularization for …

Vascular mimicry: A potential therapeutic target in breast cancer

H Chavoshi, N Poormolaie, V Vahedian… - … -Research and Practice, 2022 - Elsevier
… The ability of cancer cells to organize themselves into vascular-like structures for the …
Vasculogenic mimicry. In this review article, we tried to review the formation VM and the therapeutic

[HTML][HTML] Paradigms of vascularization in melanoma: Clinical significance and potential for therapeutic targeting

P Mabeta - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Vasculogenic mimicry (VM) is the formation of … paradigm of perfusion in melanoma following
the observation of periodic acid Schiff (PAS) stained channels [34]. Vasculogenic mimicry

Advanced research on vasculogenic mimicry in cancer

L Qiao, N Liang, J Zhang, J Xie, F Liu… - Journal of cellular …, 2015 - Wiley Online Library
Vasculogenic mimicry (VM) is a brand-new tumour vascular paradigm independent of
angiogenesis … , and contribute to finding an effective gene therapy or targeting therapy for tumours. …

Tumor plasticity allows vasculogenic mimicry, a novel form of angiogenic switch: a rose by any other name?

MJ Bissell - The American journal of pathology, 1999 - ASIP
… with a phenomenon that is best characterized as “vasculogenic mimicry.” 3 As such, the results
… In essence, these findings add a new layer of complexity to the accepted paradigm for the …

Vasculogenic mimicry and tumor angiogenesis

R Folberg, MJC Hendrix, AJ Maniotis - The American journal of pathology, 2000 - Elsevier
… that express vasculogenic mimicry. Although it is not known if therapeutic strategies targeting
… It is a well-accepted paradigm that tumors recruit new blood vessels from the existing …