Dual pathway inhibition for vascular protection in patients with atherosclerotic disease: rationale and review of the evidence

JI Weitz, DJ Angiolillo, T Geisler… - Thrombosis and …, 2020 - thieme-connect.com
… effective than inhibiting either pathway alone. The benefit of … where the combination of
rivaroxaban vascular dose (2.5 mg twice … vascular dose was developed for vascular protection in a …

Vascular protection by dietary polyphenols

JC Stoclet, T Chataigneau, M Ndiaye, MH Oak… - European journal of …, 2004 - Elsevier
… confer cardiovascular protection, improvement of the endothelial function and inhibition of
… kinase (p38 MAPK) pathway activation (leading to inhibition of platelet-derived growth factor …

Statins and their role in vascular protection

JC Mason - Clinical Science, 2003 - portlandpress.com
… the failure of statins to protect against ischaemic CVA or to inhibit leucocyte–EC interactions
… the PI3-K/Akt pathway, resulting in phosphorylation of eNOS, inhibition of apoptosis and …

Signaling mechanisms mediating vascular protective actions of vascular endothelial growth factor

I Zachary - American Journal of Physiology-Cell Physiology, 2001 - journals.physiology.org
… that mediate the inhibition of vascular smooth muscle cell … of the vascular protection model.
Accordingly, the main focus will be on the signaling pathways involved in vascular protective

Vascular protection: a novel nonangiogenic cardiovascular role for vascular endothelial growth factor

I Zachary, A Mathur, S Yla-Herttuala… - … , and vascular biology, 2000 - Am Heart Assoc
… perform vascular protective roles, including the inhibition of … also acts as a vascular protective
factor via increased NO … signaling pathways to enhance endothelial integrity, inhibit SMC …

The “CholesteROR” protective pathway in the vascular system

F Boukhtouche, J Mariani, A Tedgui - … , thrombosis, and vascular …, 2004 - Am Heart Assoc
inhibit inflammatory responses in vascular SMC by transcriptional regulation of I-κBα gene,
the inhibitor … of RORα result from the inhibition of NF-κB signaling pathway by inducing I-κBα …

Vagal stimulation triggers peripheral vascular protection through the cholinergic anti-inflammatory pathway in a rat model of myocardial ischemia/reperfusion

M Zhao, X He, XY Bi, XJ Yu, W Gil Wier… - Basic research in …, 2013 - Springer
… were inhibited by atropine or methyllycaconitine, indicating that functional protection was …
Finally, VNS increased STAT3 phosphorylation and inhibited NF-κB activation in mesenteric …

Protection of vascular cells from oxidative stress by proteasome inhibition depends on Nrf2

H Dreger, K Westphal, N Wilck… - Cardiovascular …, 2010 - academic.oup.com
inhibitor-mediated induction of SOD1 and HO1 was accompanied by protection of vascular
cells … for proteasome inhibitor-mediated protection of vascular cells against oxidative stress. …

Beyond lipid lowering: the role of statins in vascular protection

JK Liao - International journal of cardiology, 2002 - Elsevier
… , this pathway activates eNOS much more rapidly than Rho geranylgeranylation inhibition
and … Studies suggest that statins can inhibit vascular proliferative disease and platelet-derived …

Ginkgo biloba extract in vascular protection: molecular mechanisms and clinical applications

J Tian, Y Liu, K Chen - Current Vascular Pharmacology, 2017 - ingentaconnect.com
… /ml)induced human platelet aggregation with an inhibitory ratio of 43.2% and 51.3%,
respectively, which was associated with the inhibition of the PI3k/Akt pathway. In addition, treatment …